You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output.
Click here to find out more.
X Demographics
Mendeley readers
Attention Score in Context
| Title |
The Antioxidant Effects of the Flavonoids Rutin and Quercetin Inhibit Oxaliplatin-Induced Chronic Painful Peripheral Neuropathy
|
|---|---|
| Published in |
Molecular Pain, January 2013
|
| DOI | 10.1186/1744-8069-9-53 |
| Pubmed ID | |
| Authors |
Maria Isabel Azevedo, Anamaria Falcão Pereira, Ricardo Braz Nogueira, Flávio Esmeraldo Rolim, Gerly AC Brito, Deysi Viviana T Wong, Roberto CP Lima-Júnior, Ronaldo de Albuquerque Ribeiro, Mariana Lima Vale |
| Abstract |
Oxaliplatin, the third-generation platinum compound, has evolved as one of the most important therapeutic agents in colorectal cancer chemotherapy. The main limiting factor in oxaliplatin treatment is painful neuropathy that is difficult to treat. This side effect has been studied for several years, but its full mechanism is still inconclusive, and effective treatment does not exist. Data suggest that oxaliplatin's initial neurotoxic effect is peripheral and oxidative stress-dependent. A spinal target is also suggested in its mechanism of action. The flavonoids rutin and quercetin have been described as cell-protecting agents because of their antioxidant, antinociceptive, and anti-inflammatory actions. We proposed a preventive effect of these agents on oxaliplatin-induced painful peripheral neuropathy based on their antioxidant properties. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 184 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Lebanon | 1 | <1% |
| Unknown | 183 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 36 | 20% |
| Student > Ph. D. Student | 34 | 18% |
| Researcher | 17 | 9% |
| Student > Bachelor | 15 | 8% |
| Professor > Associate Professor | 8 | 4% |
| Other | 35 | 19% |
| Unknown | 39 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 33 | 18% |
| Medicine and Dentistry | 26 | 14% |
| Pharmacology, Toxicology and Pharmaceutical Science | 24 | 13% |
| Biochemistry, Genetics and Molecular Biology | 13 | 7% |
| Neuroscience | 11 | 6% |
| Other | 25 | 14% |
| Unknown | 52 | 28% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 November 2018.
All research outputs
#20,657,128
of 25,374,917 outputs
Outputs from Molecular Pain
#477
of 669 outputs
Outputs of similar age
#228,822
of 289,007 outputs
Outputs of similar age from Molecular Pain
#36
of 41 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
So far Altmetric has tracked 669 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.1. This one is in the 11th percentile – i.e., 11% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 289,007 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 41 others from the same source and published within six weeks on either side of this one. This one is in the 4th percentile – i.e., 4% of its contemporaries scored the same or lower than it.