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Diabetes impairs an interleukin-1β-dependent pathway that enhances neurite outgrowth through JAK/STAT3 modulation of mitochondrial bioenergetics in adult sensory neurons

Overview of attention for article published in Molecular Brain, January 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (85th percentile)
  • High Attention Score compared to outputs of the same age and source (93rd percentile)

Mentioned by

blogs
1 blog
twitter
4 tweeters

Citations

dimensions_citation
23 Dimensions

Readers on

mendeley
53 Mendeley
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Title
Diabetes impairs an interleukin-1β-dependent pathway that enhances neurite outgrowth through JAK/STAT3 modulation of mitochondrial bioenergetics in adult sensory neurons
Published in
Molecular Brain, January 2013
DOI 10.1186/1756-6606-6-45
Pubmed ID
Authors

Ali Saleh, Subir K Roy Chowdhury, Darrell R Smith, Savitha Balakrishnan, Lori Tessler, Emily Schartner, Andre Bilodeau, Randy Van Der Ploeg, Paul Fernyhough

Abstract

A luminex-based screen of cytokine expression in dorsal root ganglia (DRG) and nerve of type 1 diabetic rodents revealed interleukin-1 (IL-1α) and IL-1β to be significantly depressed. We, therefore, tested the hypothesis that impaired IL-1α and IL-1β expression in DRG may contribute to aberrant axon regeneration and plasticity seen in diabetic sensory neuropathy. In addition, we determined if these cytokines could optimize mitochondrial bioenergetics since mitochondrial dysfunction is a key etiological factor in diabetic neuropathy.

Twitter Demographics

The data shown below were collected from the profiles of 4 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 53 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Unknown 52 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 10 19%
Researcher 10 19%
Student > Bachelor 5 9%
Professor 4 8%
Student > Postgraduate 3 6%
Other 8 15%
Unknown 13 25%
Readers by discipline Count As %
Medicine and Dentistry 11 21%
Biochemistry, Genetics and Molecular Biology 9 17%
Agricultural and Biological Sciences 9 17%
Nursing and Health Professions 3 6%
Neuroscience 2 4%
Other 6 11%
Unknown 13 25%

Attention Score in Context

This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 October 2013.
All research outputs
#2,868,730
of 20,374,295 outputs
Outputs from Molecular Brain
#182
of 1,026 outputs
Outputs of similar age
#30,977
of 207,787 outputs
Outputs of similar age from Molecular Brain
#4
of 44 outputs
Altmetric has tracked 20,374,295 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,026 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.1. This one has done well, scoring higher than 82% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 207,787 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 85% of its contemporaries.
We're also able to compare this research output to 44 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 93% of its contemporaries.