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Emerging pharmacotherapy for cancer patients with cognitive dysfunction

Overview of attention for article published in BMC Neurology, October 2013
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Title
Emerging pharmacotherapy for cancer patients with cognitive dysfunction
Published in
BMC Neurology, October 2013
DOI 10.1186/1471-2377-13-153
Pubmed ID
Authors

Justin Davis, Fiona M Ahlberg, Michael Berk, David M Ashley, Mustafa Khasraw

Abstract

Advances in the diagnosis and multi-modality treatment of cancer have increased survival rates for many cancer types leading to an increasing load of long-term sequelae of therapy, including that of cognitive dysfunction. The cytotoxic nature of chemotherapeutic agents may also reduce neurogenesis, a key component of the physiology of memory and cognition, with ramifications for the patient's mood and other cognition disorders. Similarly radiotherapy employed as a therapeutic or prophylactic tool in the treatment of primary or metastatic disease may significantly affect cognition. A number of emerging pharmacotherapies are under investigation for the treatment of cognitive dysfunction experienced by cancer patients. Recent data from clinical trials is reviewed involving the stimulants modafinil and methylphenidate, mood stabiliser lithium, anti-Alzheimer's drugs memantine and donepezil, as well as other agents which are currently being explored within dementia, animal, and cell culture models to evaluate their use in treating cognitive dysfunction.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 123 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 123 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 21 17%
Student > Master 19 15%
Student > Ph. D. Student 14 11%
Researcher 11 9%
Other 9 7%
Other 31 25%
Unknown 18 15%
Readers by discipline Count As %
Medicine and Dentistry 34 28%
Psychology 15 12%
Nursing and Health Professions 10 8%
Neuroscience 10 8%
Agricultural and Biological Sciences 9 7%
Other 24 20%
Unknown 21 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 December 2021.
All research outputs
#15,309,583
of 22,769,322 outputs
Outputs from BMC Neurology
#1,478
of 2,428 outputs
Outputs of similar age
#130,586
of 212,081 outputs
Outputs of similar age from BMC Neurology
#45
of 70 outputs
Altmetric has tracked 22,769,322 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,428 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.7. This one is in the 26th percentile – i.e., 26% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 212,081 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 70 others from the same source and published within six weeks on either side of this one. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.