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The Campylobacter jejuniCiaD effector protein activates MAP kinase signaling pathways and is required for the development of disease

Overview of attention for article published in Cell Communication and Signaling, October 2013
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Title
The Campylobacter jejuniCiaD effector protein activates MAP kinase signaling pathways and is required for the development of disease
Published in
Cell Communication and Signaling, October 2013
DOI 10.1186/1478-811x-11-79
Pubmed ID
Authors

Derrick R Samuelson, Tyson P Eucker, Julia A Bell, Leslie Dybas, Linda S Mansfield, Michael E Konkel

Abstract

Enteric pathogens utilize a distinct set of proteins to modulate host cell signaling events that promote host cell invasion, induction of the inflammatory response, and intracellular survival. Human infection with Campylobacter jejuni, the causative agent of campylobacteriosis, is characterized by diarrhea containing blood and leukocytes. The clinical presentation of acute disease, which is consistent with cellular invasion, requires the delivery of the Campylobacter invasion antigens (Cia) to the cytosol of host cells via a flagellar Type III Secretion System (T3SS). We identified a novel T3SS effector protein, which we termed CiaD that is exported from the C. jejuni flagellum and delivered to the cytosol of host cells.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 45 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Hungary 1 2%
United States 1 2%
France 1 2%
Unknown 42 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 20%
Student > Bachelor 7 16%
Student > Master 7 16%
Researcher 5 11%
Student > Doctoral Student 4 9%
Other 4 9%
Unknown 9 20%
Readers by discipline Count As %
Agricultural and Biological Sciences 14 31%
Biochemistry, Genetics and Molecular Biology 9 20%
Immunology and Microbiology 5 11%
Veterinary Science and Veterinary Medicine 3 7%
Environmental Science 1 2%
Other 2 4%
Unknown 11 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 October 2013.
All research outputs
#20,207,295
of 22,727,570 outputs
Outputs from Cell Communication and Signaling
#907
of 980 outputs
Outputs of similar age
#184,641
of 211,629 outputs
Outputs of similar age from Cell Communication and Signaling
#7
of 10 outputs
Altmetric has tracked 22,727,570 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 980 research outputs from this source. They receive a mean Attention Score of 4.0. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 211,629 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than 3 of them.