Title |
Bluetongue virus infection induces aberrant mitosis in mammalian cells
|
---|---|
Published in |
Virology Journal, October 2013
|
DOI | 10.1186/1743-422x-10-319 |
Pubmed ID | |
Authors |
Andrew E Shaw, Anke Brüning-Richardson, Ewan E Morrison, Jacquelyn Bond, Jennifer Simpson, Natalie Ross-Smith, Oya Alpar, Peter PC Mertens, Paul Monaghan |
Abstract |
Bluetongue virus (BTV) is an arbovirus that is responsible for 'bluetongue', an economically important disease of livestock. Although BTV is well characterised at the protein level, less is known regarding its interaction with host cells. During studies of virus inclusion body formation we observed what appeared to be a large proportion of cells in mitosis. Although the modulation of the cell cycle is well established for many viruses, this was a novel observation for BTV. We therefore undertook a study to reveal in more depth the impact of BTV upon cell division. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 3 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 67% |
Science communicators (journalists, bloggers, editors) | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 21 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 6 | 29% |
Student > Ph. D. Student | 5 | 24% |
Professor | 2 | 10% |
Student > Master | 2 | 10% |
Student > Bachelor | 1 | 5% |
Other | 0 | 0% |
Unknown | 5 | 24% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 8 | 38% |
Veterinary Science and Veterinary Medicine | 4 | 19% |
Immunology and Microbiology | 1 | 5% |
Psychology | 1 | 5% |
Medicine and Dentistry | 1 | 5% |
Other | 1 | 5% |
Unknown | 5 | 24% |