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HIV-1 Tat protein binds to TLR4-MD2 and signals to induce TNF-α and IL-10

Overview of attention for article published in Retrovirology, October 2013
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Title
HIV-1 Tat protein binds to TLR4-MD2 and signals to induce TNF-α and IL-10
Published in
Retrovirology, October 2013
DOI 10.1186/1742-4690-10-123
Pubmed ID
Authors

Nawal Ben Haij, Kaoutar Leghmari, Rémi Planès, Nathalie Thieblemont, Elmostafa Bahraoui

Abstract

HIV-1 infection results in hyper-immune activation and immunological disorders as early as the asymptomatic stage. Here, we hypothesized that during early HIV-1 infection, HIV-1 Tat protein acts on monocytes/macrophages to induce anti-inflammatory and proinflammatory cytokines and participates in immune dysregulation.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 42 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Canada 2 5%
Unknown 40 95%

Demographic breakdown

Readers by professional status Count As %
Student > Master 11 26%
Student > Ph. D. Student 7 17%
Researcher 6 14%
Student > Bachelor 3 7%
Student > Doctoral Student 2 5%
Other 3 7%
Unknown 10 24%
Readers by discipline Count As %
Agricultural and Biological Sciences 15 36%
Biochemistry, Genetics and Molecular Biology 6 14%
Immunology and Microbiology 5 12%
Pharmacology, Toxicology and Pharmaceutical Science 1 2%
Arts and Humanities 1 2%
Other 4 10%
Unknown 10 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 September 2022.
All research outputs
#16,665,631
of 24,520,187 outputs
Outputs from Retrovirology
#804
of 1,136 outputs
Outputs of similar age
#135,798
of 218,383 outputs
Outputs of similar age from Retrovirology
#32
of 53 outputs
Altmetric has tracked 24,520,187 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,136 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.1. This one is in the 17th percentile – i.e., 17% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 218,383 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 53 others from the same source and published within six weeks on either side of this one. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.