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Systematic design methodology for robust genetic transistors based on I/O specifications via promoter-RBS libraries

Overview of attention for article published in BMC Systems Biology, October 2013
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Title
Systematic design methodology for robust genetic transistors based on I/O specifications via promoter-RBS libraries
Published in
BMC Systems Biology, October 2013
DOI 10.1186/1752-0509-7-109
Pubmed ID
Authors

Yi-Ying Lee, Chih-Yuan Hsu, Ling-Jiun Lin, Chih-Chun Chang, Hsiao-Chun Cheng, Tsung-Hsien Yeh, Rei-Hsing Hu, Che Lin, Zhen Xie, Bor-Sen Chen

Abstract

Synthetic genetic transistors are vital for signal amplification and switching in genetic circuits. However, it is still problematic to efficiently select the adequate promoters, Ribosome Binding Sides (RBSs) and inducer concentrations to construct a genetic transistor with the desired linear amplification or switching in the Input/Output (I/O) characteristics for practical applications.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 4 14%
Chile 1 4%
China 1 4%
Unknown 22 79%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 32%
Researcher 7 25%
Student > Bachelor 4 14%
Student > Master 3 11%
Other 2 7%
Other 3 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 12 43%
Biochemistry, Genetics and Molecular Biology 8 29%
Computer Science 2 7%
Sports and Recreations 1 4%
Social Sciences 1 4%
Other 2 7%
Unknown 2 7%