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Antiviral activity of α-helical stapled peptides designed from the HIV-1 capsid dimerization domain

Overview of attention for article published in Retrovirology, May 2011
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (90th percentile)
  • High Attention Score compared to outputs of the same age and source (84th percentile)

Mentioned by

news
1 news outlet
patent
3 patents

Citations

dimensions_citation
63 Dimensions

Readers on

mendeley
72 Mendeley
citeulike
1 CiteULike
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Title
Antiviral activity of α-helical stapled peptides designed from the HIV-1 capsid dimerization domain
Published in
Retrovirology, May 2011
DOI 10.1186/1742-4690-8-28
Pubmed ID
Authors

Hongtao Zhang, Francesca Curreli, Xihui Zhang, Shibani Bhattacharya, Abdul A Waheed, Alan Cooper, David Cowburn, Eric O Freed, Asim K Debnath

Abstract

The C-terminal domain (CTD) of HIV-1 capsid (CA), like full-length CA, forms dimers in solution and CTD dimerization is a major driving force in Gag assembly and maturation. Mutations of the residues at the CTD dimer interface impair virus assembly and render the virus non-infectious. Therefore, the CTD represents a potential target for designing anti-HIV-1 drugs.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 72 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Italy 1 1%
Uruguay 1 1%
United Kingdom 1 1%
Canada 1 1%
United States 1 1%
Unknown 67 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 20 28%
Researcher 15 21%
Professor > Associate Professor 5 7%
Student > Bachelor 5 7%
Student > Master 5 7%
Other 13 18%
Unknown 9 13%
Readers by discipline Count As %
Chemistry 22 31%
Agricultural and Biological Sciences 17 24%
Biochemistry, Genetics and Molecular Biology 9 13%
Medicine and Dentistry 5 7%
Pharmacology, Toxicology and Pharmaceutical Science 3 4%
Other 6 8%
Unknown 10 14%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 December 2020.
All research outputs
#2,272,945
of 22,729,647 outputs
Outputs from Retrovirology
#98
of 1,105 outputs
Outputs of similar age
#10,529
of 110,216 outputs
Outputs of similar age from Retrovirology
#2
of 13 outputs
Altmetric has tracked 22,729,647 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,105 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.0. This one has done particularly well, scoring higher than 91% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 110,216 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 90% of its contemporaries.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 84% of its contemporaries.