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Microbicide excipients can greatly increase susceptibility to genital herpes transmission in the mouse

Overview of attention for article published in BMC Infectious Diseases, November 2010
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (88th percentile)
  • High Attention Score compared to outputs of the same age and source (93rd percentile)

Mentioned by

news
1 news outlet
twitter
1 tweeter
patent
1 patent

Citations

dimensions_citation
46 Dimensions

Readers on

mendeley
29 Mendeley
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Title
Microbicide excipients can greatly increase susceptibility to genital herpes transmission in the mouse
Published in
BMC Infectious Diseases, November 2010
DOI 10.1186/1471-2334-10-331
Pubmed ID
Authors

Thomas R Moench, Russell J Mumper, Timothy E Hoen, Mianmian Sun, Richard A Cone

Abstract

Several active ingredients proposed as vaginal microbicides have been shown paradoxically to increase susceptibility to infection in mouse genital herpes (HSV-2) vaginal susceptibility models and in clinical trials. In addition, "inactive ingredients" (or excipients) used in topical products to formulate and deliver the active ingredient might also cause epithelial toxicities that increase viral susceptibility. However, excipients have not previously been tested in susceptibility models.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 29 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Australia 1 3%
Unknown 28 97%

Demographic breakdown

Readers by professional status Count As %
Other 6 21%
Researcher 4 14%
Student > Ph. D. Student 4 14%
Professor > Associate Professor 3 10%
Student > Master 3 10%
Other 7 24%
Unknown 2 7%
Readers by discipline Count As %
Medicine and Dentistry 8 28%
Biochemistry, Genetics and Molecular Biology 6 21%
Chemical Engineering 2 7%
Nursing and Health Professions 2 7%
Pharmacology, Toxicology and Pharmaceutical Science 2 7%
Other 7 24%
Unknown 2 7%

Attention Score in Context

This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 June 2022.
All research outputs
#2,184,944
of 21,390,067 outputs
Outputs from BMC Infectious Diseases
#641
of 7,301 outputs
Outputs of similar age
#22,862
of 208,666 outputs
Outputs of similar age from BMC Infectious Diseases
#40
of 566 outputs
Altmetric has tracked 21,390,067 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 7,301 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.2. This one has done particularly well, scoring higher than 91% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 208,666 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 566 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 93% of its contemporaries.