Title |
MicroRNA-124-3p inhibits cell migration and invasion in bladder cancer cells by targeting ROCK1
|
---|---|
Published in |
Journal of Translational Medicine, November 2013
|
DOI | 10.1186/1479-5876-11-276 |
Pubmed ID | |
Authors |
Xianglai Xu, Shiqi Li, Yiwei Lin, Hong Chen, Zhenghui Hu, Yeqing Mao, Xin Xu, Jian Wu, Yi Zhu, Xiangyi Zheng, Jindan Luo, Liping Xie |
Abstract |
Increasing evidence has suggested that dysregulation of certain microRNAs (miRNAs) may contribute to human disease including carcinogenesis and tumor metastasis in human. miR-124-3p is down-regulated in various cancers, and modulates proliferation and aggressiveness of cancer cells. However, the roles of miR-124-3p in human bladder cancer are elusive. Thus, this study was conducted to investigate the biological functions and its molecular mechanisms of miR-124-3p in human bladder cancer cell lines, discussing whether it has a potential to be a therapeutic biomarker of bladder cancer. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Portugal | 1 | 2% |
Unknown | 53 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 11 | 20% |
Student > Ph. D. Student | 11 | 20% |
Student > Master | 7 | 13% |
Student > Doctoral Student | 4 | 7% |
Student > Bachelor | 3 | 6% |
Other | 4 | 7% |
Unknown | 14 | 26% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 13 | 24% |
Biochemistry, Genetics and Molecular Biology | 11 | 20% |
Medicine and Dentistry | 7 | 13% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 2% |
Nursing and Health Professions | 1 | 2% |
Other | 4 | 7% |
Unknown | 17 | 31% |