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Mendeley readers
| Title |
Estrogen replacement modulates voltage-gated potassium channels in rat presympathetic paraventricular nucleus neurons
|
|---|---|
| Published in |
BMC Neuroscience, November 2013
|
| DOI | 10.1186/1471-2202-14-134 |
| Pubmed ID | |
| Authors |
Seul Ki Lee, Pan Dong Ryu, So Yeong Lee |
| Abstract |
The hypothalamic paraventricular nucleus (PVN) is an important site in the regulation of the autonomic nervous system. Specifically, PVN neurons projecting to the rostral ventrolateral medulla (PVN-RVLM) play a regulatory role in the determination of the sympathetic outflow in the cardiovascular system. In the PVN-RVLM neurons, the estrogen receptor β is expressed. However, to date, the effects of estrogen on PVN-RVLM neurons have not been reported. The present study investigated estrogen-mediated modulation of two voltage-gated potassium channel (Kv) subunits, Kv4.2 and Kv4.3, that are expressed predominantly in PVN neurons and the functional current of Kv4.2 and Kv4.3, the transient outward potassium current (IA). |
Mendeley readers
The data shown below were compiled from readership statistics for 18 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 6% |
| Unknown | 17 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 5 | 28% |
| Student > Ph. D. Student | 3 | 17% |
| Other | 2 | 11% |
| Student > Postgraduate | 2 | 11% |
| Professor | 1 | 6% |
| Other | 3 | 17% |
| Unknown | 2 | 11% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 5 | 28% |
| Medicine and Dentistry | 3 | 17% |
| Neuroscience | 3 | 17% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 11% |
| Psychology | 1 | 6% |
| Other | 2 | 11% |
| Unknown | 2 | 11% |