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Decreased plasticity of coreceptor use by CD4-independent SIV Envs that emerge in vivo

Overview of attention for article published in Retrovirology, November 2013
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Title
Decreased plasticity of coreceptor use by CD4-independent SIV Envs that emerge in vivo
Published in
Retrovirology, November 2013
DOI 10.1186/1742-4690-10-133
Pubmed ID
Authors

Nicholas Francella, Sarah TC Elliott, Yanjie Yi, Sarah E Gwyn, Alexandra M Ortiz, Bing Li, Guido Silvestri, Mirko Paiardini, Cynthia A Derdeyn, Ronald G Collman

Abstract

HIV and SIV generally require CD4 binding prior to coreceptor engagement, but Env can acquire the ability to use CCR5 independently of CD4 under various circumstances. The ability to use CCR5 coupled with low-to-absent CD4 levels is associated with enhanced macrophage infection and increased neutralization sensitivity, but the additional features of these Envs that may affect cell targeting is not known.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 12 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 12 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 50%
Student > Ph. D. Student 3 25%
Student > Master 1 8%
Unknown 2 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 6 50%
Immunology and Microbiology 2 17%
Business, Management and Accounting 1 8%
Veterinary Science and Veterinary Medicine 1 8%
Medicine and Dentistry 1 8%
Other 0 0%
Unknown 1 8%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 November 2013.
All research outputs
#18,353,475
of 22,729,647 outputs
Outputs from Retrovirology
#955
of 1,105 outputs
Outputs of similar age
#157,968
of 212,425 outputs
Outputs of similar age from Retrovirology
#45
of 56 outputs
Altmetric has tracked 22,729,647 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,105 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.0. This one is in the 3rd percentile – i.e., 3% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 212,425 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 56 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.