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Temporal evaluation of commitment to sexual development in Plasmodium falciparum

Overview of attention for article published in Malaria Journal, April 2013
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Title
Temporal evaluation of commitment to sexual development in Plasmodium falciparum
Published in
Malaria Journal, April 2013
DOI 10.1186/1475-2875-12-134
Pubmed ID
Authors

Christopher L Peatey, Matthew WA Dixon, Donald L Gardiner, Katharine R Trenholme

Abstract

The production of gametocytes is essential for transmission of malaria parasites from the mammalian host to the mosquito vector. However the process by which the asexual blood-stage parasite undergoes commitment to sexual development is not well understood. This process is known to be sensitive to environmental stimuli and it has been suggested that a G protein dependent system may mediate the switch, but there is little evidence that the Plasmodium falciparum genome encodes heterotrimeric G proteins. Previous studies have indicated that the malaria parasite can interact with endogenous erythrocyte G proteins, and other components of the cyclic nucleotide pathway have been identified in P. falciparum. Also, the polypeptide cholera toxin, which induces commitment to gametocytogenesis is known to catalyze the ADP-ribosylation of the α(s) class of heterotrimeric G protein α subunits in mammalian systems has been reported to detect a number of G(α) subunits in P. falciparum-infected red cells.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 40 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Ghana 1 3%
Switzerland 1 3%
Unknown 38 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 13 33%
Student > Master 7 18%
Researcher 7 18%
Other 2 5%
Student > Bachelor 2 5%
Other 5 13%
Unknown 4 10%
Readers by discipline Count As %
Agricultural and Biological Sciences 19 48%
Biochemistry, Genetics and Molecular Biology 5 13%
Immunology and Microbiology 4 10%
Chemistry 3 8%
Environmental Science 1 3%
Other 4 10%
Unknown 4 10%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 November 2013.
All research outputs
#18,353,475
of 22,729,647 outputs
Outputs from Malaria Journal
#5,024
of 5,549 outputs
Outputs of similar age
#148,535
of 196,476 outputs
Outputs of similar age from Malaria Journal
#67
of 75 outputs
Altmetric has tracked 22,729,647 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,549 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one is in the 4th percentile – i.e., 4% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 196,476 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 75 others from the same source and published within six weeks on either side of this one. This one is in the 2nd percentile – i.e., 2% of its contemporaries scored the same or lower than it.