Title |
Superinfection with drug-resistant HIV is rare and does not contribute substantially to therapy failure in a large European cohort
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Published in |
BMC Infectious Diseases, November 2013
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DOI | 10.1186/1471-2334-13-537 |
Pubmed ID | |
Authors |
István Bartha, Matthias Assel, Peter MA Sloot, Maurizio Zazzi, Carlo Torti, Eugen Schülter, Andrea De Luca, Anders Sönnerborg, Ana B Abecasis, Kristel Van Laethem, Andrea Rosi, Jenny Svärd, Roger Paredes, David AMC van de Vijver, Anne-Mieke Vandamme, Viktor Müller |
Abstract |
Superinfection with drug resistant HIV strains could potentially contribute to compromised therapy in patients initially infected with drug-sensitive virus and receiving antiretroviral therapy. To investigate the importance of this potential route to drug resistance, we developed a bioinformatics pipeline to detect superinfection from routinely collected genotyping data, and assessed whether superinfection contributed to increased drug resistance in a large European cohort of viremic, drug treated patients. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Mexico | 2 | 67% |
United States | 1 | 33% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 3 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Hungary | 1 | 2% |
Germany | 1 | 2% |
Unknown | 42 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 10 | 23% |
Student > Master | 5 | 11% |
Student > Doctoral Student | 4 | 9% |
Other | 4 | 9% |
Professor > Associate Professor | 4 | 9% |
Other | 8 | 18% |
Unknown | 9 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 9 | 20% |
Agricultural and Biological Sciences | 6 | 14% |
Computer Science | 5 | 11% |
Immunology and Microbiology | 5 | 11% |
Nursing and Health Professions | 2 | 5% |
Other | 5 | 11% |
Unknown | 12 | 27% |