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Mendeley readers
| Title |
Characterization of PfTrxR inhibitors using antimalarial assays and in silicotechniques
|
|---|---|
| Published in |
BMC Chemistry, November 2013
|
| DOI | 10.1186/1752-153x-7-175 |
| Pubmed ID | |
| Authors |
Ranjith Munigunti, Symon Gathiaka, Orlando Acevedo, Rajnish Sahu, Babu Tekwani, Angela I Calderón |
| Abstract |
The compounds 1,4-napthoquinone (1,4-NQ), bis-(2,4-dinitrophenyl)sulfide (2,4-DNPS), 4-nitrobenzothiadiazole (4-NBT), 3-dimethylaminopropiophenone (3-DAP) and menadione (MD) were tested for antimalarial activity against both chloroquine (CQ)-sensitive (D6) and chloroquine (CQ)-resistant (W2) strains of Plasmodium falciparum through an in vitro assay and also for analysis of non-covalent interactions with P. falciparum thioredoxin reductase (PfTrxR) through in silico docking studies. |
Mendeley readers
The data shown below were compiled from readership statistics for 16 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 13% |
| United States | 1 | 6% |
| Unknown | 13 | 81% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 4 | 25% |
| Student > Doctoral Student | 2 | 13% |
| Other | 2 | 13% |
| Student > Master | 2 | 13% |
| Professor | 1 | 6% |
| Other | 3 | 19% |
| Unknown | 2 | 13% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 4 | 25% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 19% |
| Chemistry | 3 | 19% |
| Agricultural and Biological Sciences | 1 | 6% |
| Medicine and Dentistry | 1 | 6% |
| Other | 1 | 6% |
| Unknown | 3 | 19% |