Title |
Molecular adaptation of telomere associated genes in mammals
|
---|---|
Published in |
BMC Ecology and Evolution, November 2013
|
DOI | 10.1186/1471-2148-13-251 |
Pubmed ID | |
Authors |
Claire C Morgan, Ann M Mc Cartney, Mark TA Donoghue, Noeleen B Loughran, Charles Spillane, Emma C Teeling, Mary J O’Connell |
Abstract |
Placental mammals display a huge range of life history traits, including size, longevity, metabolic rate and germ line generation time. Although a number of general trends have been proposed between these traits, there are exceptions that warrant further investigation. Species such as naked mole rat, human and certain bat species all exhibit extreme longevity with respect to body size. It has long been established that telomeres and telomere maintenance have a clear role in ageing but it has not yet been established whether there is evidence for adaptation in telomere maintenance proteins that could account for increased longevity in these species. |
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Mendeley readers
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