Title |
Serum heat shock protein 47 levels in patients with drug-induced lung disease
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Published in |
Respiratory Research, November 2013
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DOI | 10.1186/1465-9921-14-133 |
Pubmed ID | |
Authors |
Tomoyuki Kakugawa, Shin-ichi Yokota, Yuji Ishimatsu, Tomayoshi Hayashi, Shota Nakashima, Shintaro Hara, Noriho Sakamoto, Yasuhiro Matsuoka, Hiroshi Kubota, Mariko Mine, Hiroshi Mukae, Kazuhiro Nagata, Shigeru Kohno |
Abstract |
Heat shock protein (HSP) 47 is a collagen-specific molecular chaperone that is required for molecular maturation of various types of collagens. We recently reported that HSP47 serum levels were markedly higher in patients with acute exacerbations of idiopathic pulmonary fibrosis (IPF) when compared with patients with stable IPF, suggesting that serum HSP47 levels correlate with interstitial pneumonia activity. The aim of this study was to evaluate serum HSP47 levels in patients with drug-induced lung disease (DILD). |
X Demographics
Geographical breakdown
Country | Count | As % |
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United Kingdom | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 40 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 9 | 23% |
Researcher | 6 | 15% |
Student > Ph. D. Student | 5 | 13% |
Student > Postgraduate | 3 | 8% |
Other | 3 | 8% |
Other | 7 | 18% |
Unknown | 7 | 18% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 14 | 35% |
Agricultural and Biological Sciences | 4 | 10% |
Biochemistry, Genetics and Molecular Biology | 3 | 8% |
Social Sciences | 3 | 8% |
Business, Management and Accounting | 2 | 5% |
Other | 5 | 13% |
Unknown | 9 | 23% |