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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Exosomes are natural carriers of exogenous siRNA to human cells in vitro
|
|---|---|
| Published in |
Cell Communication and Signaling, November 2013
|
| DOI | 10.1186/1478-811x-11-88 |
| Pubmed ID | |
| Authors |
Tatyana A Shtam, Roman A Kovalev, Elena Yu Varfolomeeva, Evgeny M Makarov, Yury V Kil, Michael V Filatov |
| Abstract |
Exosomes are nano-sized vesicles of endocytic origin that are involved in cell-to-cell communication including shuttle RNA, mainly mRNA and microRNA. As exosomes naturally carry RNA between cells, these particles might be useful in gene cancer therapy to deliver therapeutic short interfering RNA (siRNA) to the target cells. Despite the promise of RNA interference (RNAi) for use in therapy, several technical obstacles must be overcome. Exogenous siRNA is prone to degradation, has a limited ability to cross cell membranes and may induce an immune response. Naturally occurring RNA carriers, such as exosomes, might provide an untapped source of effective delivery strategies. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 390 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Chile | 2 | <1% |
| United States | 2 | <1% |
| Turkey | 1 | <1% |
| Brazil | 1 | <1% |
| Canada | 1 | <1% |
| Czechia | 1 | <1% |
| Denmark | 1 | <1% |
| Belgium | 1 | <1% |
| Unknown | 380 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 85 | 22% |
| Researcher | 59 | 15% |
| Student > Bachelor | 49 | 13% |
| Student > Master | 43 | 11% |
| Student > Doctoral Student | 21 | 5% |
| Other | 38 | 10% |
| Unknown | 95 | 24% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 92 | 24% |
| Agricultural and Biological Sciences | 75 | 19% |
| Medicine and Dentistry | 29 | 7% |
| Engineering | 22 | 6% |
| Pharmacology, Toxicology and Pharmaceutical Science | 17 | 4% |
| Other | 40 | 10% |
| Unknown | 115 | 29% |
Attention Score in Context
This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 July 2020.
All research outputs
#4,159,569
of 22,731,677 outputs
Outputs from Cell Communication and Signaling
#89
of 982 outputs
Outputs of similar age
#49,012
of 302,168 outputs
Outputs of similar age from Cell Communication and Signaling
#2
of 12 outputs
Altmetric has tracked 22,731,677 research outputs across all sources so far. Compared to these this one has done well and is in the 80th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 982 research outputs from this source. They receive a mean Attention Score of 4.0. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 302,168 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 82% of its contemporaries.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 83% of its contemporaries.