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Everolimus-induced epithelial to mesenchymal transition in immortalized human renal proximal tubular epithelial cells: key role of heparanase

Overview of attention for article published in Journal of Translational Medicine, November 2013
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2 X users

Citations

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22 Dimensions

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19 Mendeley
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1 CiteULike
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Title
Everolimus-induced epithelial to mesenchymal transition in immortalized human renal proximal tubular epithelial cells: key role of heparanase
Published in
Journal of Translational Medicine, November 2013
DOI 10.1186/1479-5876-11-292
Pubmed ID
Authors

Valentina Masola, Gianluigi Zaza, Simona Granata, Giovanni Gambaro, Maurizio Onisto, Antonio Lupo

Abstract

Everolimus (EVE) is a drug widely used in several renal transplant protocols. Although characterized by a relatively low nephrotoxicity, it may induce several adverse effects including severe fibro-interstitial pneumonitis. The exact molecular/biological mechanism associated to these pro-fibrotic effects is unknown, but epithelial to mesenchymal transition (EMT) may have a central role. Additionally, heparanase, an enzyme recently associated with the progression of chronic allograft nephropathy, could contribute to activate this machinery in renal cells.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 19 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 4 21%
Professor 3 16%
Researcher 3 16%
Student > Ph. D. Student 2 11%
Professor > Associate Professor 2 11%
Other 1 5%
Unknown 4 21%
Readers by discipline Count As %
Medicine and Dentistry 4 21%
Biochemistry, Genetics and Molecular Biology 3 16%
Agricultural and Biological Sciences 2 11%
Psychology 1 5%
Nursing and Health Professions 1 5%
Other 2 11%
Unknown 6 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 December 2013.
All research outputs
#17,703,558
of 22,731,677 outputs
Outputs from Journal of Translational Medicine
#2,737
of 3,974 outputs
Outputs of similar age
#219,452
of 302,010 outputs
Outputs of similar age from Journal of Translational Medicine
#62
of 114 outputs
Altmetric has tracked 22,731,677 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,974 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.5. This one is in the 25th percentile – i.e., 25% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 302,010 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 24th percentile – i.e., 24% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 114 others from the same source and published within six weeks on either side of this one. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.