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Conjugative transfer of an IncA/C plasmid-borne blaCMY-2gene through genetic re-arrangements with an IncX1 plasmid

Overview of attention for article published in BMC Microbiology, November 2013
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Title
Conjugative transfer of an IncA/C plasmid-borne blaCMY-2gene through genetic re-arrangements with an IncX1 plasmid
Published in
BMC Microbiology, November 2013
DOI 10.1186/1471-2180-13-264
Pubmed ID
Authors

Magdalena Wiesner, Marcos Fernández-Mora, Miguel A Cevallos, Crispín Zavala-Alvarado, Mussaret B Zaidi, Edmundo Calva, Claudia Silva

Abstract

Our observation that in the Mexican Salmonella Typhimurium population none of the ST19 and ST213 strains harbored both the Salmonella virulence plasmid (pSTV) and the prevalent IncA/C plasmid (pA/C) led us to hypothesize that restriction to horizontal transfer of these plasmids existed. We designed a conjugation scheme using ST213 strain YU39 as donor of the blaCMY-2 gene (conferring resistance to ceftriaxone; CRO) carried by pA/C, and two E. coli lab strains (DH5α and HB101) and two Typhimurium ST19 strains (SO1 and LT2) carrying pSTV as recipients. The aim of this study was to determine if the genetic background of the different recipient strains affected the transfer frequencies of pA/C.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 54 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Colombia 1 2%
Portugal 1 2%
Tanzania, United Republic of 1 2%
Brazil 1 2%
Unknown 50 93%

Demographic breakdown

Readers by professional status Count As %
Researcher 17 31%
Student > Ph. D. Student 14 26%
Student > Master 4 7%
Student > Bachelor 3 6%
Professor 2 4%
Other 4 7%
Unknown 10 19%
Readers by discipline Count As %
Agricultural and Biological Sciences 13 24%
Biochemistry, Genetics and Molecular Biology 11 20%
Immunology and Microbiology 4 7%
Veterinary Science and Veterinary Medicine 3 6%
Medicine and Dentistry 3 6%
Other 6 11%
Unknown 14 26%