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CSF Presenilin-1 complexes are increased in Alzheimer’s disease

Overview of attention for article published in Acta Neuropathologica Communications, August 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (86th percentile)
  • Good Attention Score compared to outputs of the same age and source (75th percentile)

Mentioned by

blogs
1 blog
twitter
2 tweeters

Citations

dimensions_citation
16 Dimensions

Readers on

mendeley
34 Mendeley
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Title
CSF Presenilin-1 complexes are increased in Alzheimer’s disease
Published in
Acta Neuropathologica Communications, August 2013
DOI 10.1186/2051-5960-1-46
Pubmed ID
Authors

María-Salud García-Ayllón, María-Letizia Campanari, Gunnar Brinkmalm, Alberto Rábano, Jordi Alom, Carlos A Saura, Niels Andreasen, Kaj Blennow, Javier Sáez-Valero

Abstract

Presenilin-1 (PS1) is the active component of the amyloid precursor protein cleaving γ-secretase complex. PS1 protein is a transmembrane protein containing multiple hydrophobic regions which presence in cerebrospinal fluid (CSF) has not been measured to date. This study assesses whether PS1 and other components of the γ-secretase complex are present in CSF.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 34 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Belgium 1 3%
Unknown 33 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 12 35%
Student > Ph. D. Student 7 21%
Student > Postgraduate 3 9%
Student > Doctoral Student 2 6%
Student > Master 2 6%
Other 6 18%
Unknown 2 6%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 9 26%
Neuroscience 8 24%
Agricultural and Biological Sciences 7 21%
Business, Management and Accounting 2 6%
Medicine and Dentistry 1 3%
Other 1 3%
Unknown 6 18%

Attention Score in Context

This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 January 2014.
All research outputs
#2,342,476
of 17,365,229 outputs
Outputs from Acta Neuropathologica Communications
#526
of 1,061 outputs
Outputs of similar age
#36,053
of 271,744 outputs
Outputs of similar age from Acta Neuropathologica Communications
#9
of 33 outputs
Altmetric has tracked 17,365,229 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,061 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.4. This one has gotten more attention than average, scoring higher than 50% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 271,744 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 33 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 75% of its contemporaries.