Title |
Stereotactic body radiation therapy (SBRT) for lung malignancies: preliminary toxicity results using a flattening filter-free linear accelerator operating at 2400 monitor units per minute
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Published in |
Radiation Oncology, November 2013
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DOI | 10.1186/1748-717x-8-273 |
Pubmed ID | |
Authors |
Brendan M Prendergast, Michael C Dobelbower, James A Bonner, Richard A Popple, Craig J Baden, Douglas J Minnich, Robert J Cerfolio, Sharon A Spencer, John B Fiveash |
Abstract |
Flattening filter-free (FFF) linear accelerators (linacs) are capable of delivering dose rates more than 4-times higher than conventional linacs during SBRT treatments, causing some to speculate whether the higher dose rate leads to increased toxicity owing to radiobiological dose rate effects. Despite wide clinical use of this emerging technology, clinical toxicity data for FFF SBRT are lacking. In this retrospective study, we report the acute and late toxicities observed in our lung radiosurgery experience using a FFF linac operating at 2400 MU/min. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Scientists | 1 | 100% |
Mendeley readers
Geographical breakdown
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Unknown | 40 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 11 | 28% |
Researcher | 6 | 15% |
Other | 5 | 13% |
Student > Ph. D. Student | 3 | 8% |
Student > Doctoral Student | 2 | 5% |
Other | 5 | 13% |
Unknown | 8 | 20% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 13 | 33% |
Veterinary Science and Veterinary Medicine | 1 | 3% |
Immunology and Microbiology | 1 | 3% |
Business, Management and Accounting | 1 | 3% |
Other | 2 | 5% |
Unknown | 9 | 23% |