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Genetic engineering of Yarrowia lipolytica for enhanced production of trans-10, cis-12 conjugated linoleic acid

Overview of attention for article published in Microbial Cell Factories, July 2013
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  • Good Attention Score compared to outputs of the same age (73rd percentile)
  • Average Attention Score compared to outputs of the same age and source

Mentioned by

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2 X users
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1 patent

Citations

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57 Dimensions

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74 Mendeley
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Title
Genetic engineering of Yarrowia lipolytica for enhanced production of trans-10, cis-12 conjugated linoleic acid
Published in
Microbial Cell Factories, July 2013
DOI 10.1186/1475-2859-12-70
Pubmed ID
Authors

Baixi Zhang, Haiqin Chen, Min Li, Zhennan Gu, Yuanda Song, Colin Ratledge, Yong Q Chen, Hao Zhang, Wei Chen

Abstract

Conjugated linoleic acid (CLA) has been extensively studied for decades because of its health benefits including cancer prevention, anti-atherogenic and anti-obesity effects, and modulation of the immune system. We previously described the production of trans-10, cis-12 CLA in Yarrowia lipolytica by expressing the gene coding for linoleic acid isomerase from Propionibacterium acnes (pai). However the stable strain produced CLA at about 0.08% of dry cell weight (DCW), a level of production which was not high enough for practical applications. The goal of the present study was to enhance production of CLA by genetic engineering of Y. lipolytica strains.

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X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 74 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 1%
Indonesia 1 1%
France 1 1%
Austria 1 1%
Japan 1 1%
Unknown 69 93%

Demographic breakdown

Readers by professional status Count As %
Researcher 17 23%
Student > Ph. D. Student 14 19%
Student > Bachelor 8 11%
Student > Master 5 7%
Professor 4 5%
Other 11 15%
Unknown 15 20%
Readers by discipline Count As %
Agricultural and Biological Sciences 22 30%
Biochemistry, Genetics and Molecular Biology 14 19%
Engineering 4 5%
Medicine and Dentistry 3 4%
Chemical Engineering 2 3%
Other 9 12%
Unknown 20 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 June 2022.
All research outputs
#6,754,462
of 25,374,647 outputs
Outputs from Microbial Cell Factories
#440
of 1,823 outputs
Outputs of similar age
#53,052
of 206,371 outputs
Outputs of similar age from Microbial Cell Factories
#7
of 11 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one has received more attention than most of these and is in the 73rd percentile.
So far Altmetric has tracked 1,823 research outputs from this source. They receive a mean Attention Score of 4.9. This one has done well, scoring higher than 75% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 206,371 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.