Title |
Design of the PRINCESS trial: pre-hospital resuscitation intra-nasal cooling effectiveness survival study (PRINCESS)
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Published in |
BMC Emergency Medicine, November 2013
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DOI | 10.1186/1471-227x-13-21 |
Pubmed ID | |
Authors |
Per Nordberg, Fabio Silvio Taccone, Maaret Castren, Anatolij Truhlár, Didier Desruelles, Sune Forsberg, Jacob Hollenberg, Jean-Louis Vincent, Leif Svensoon |
Abstract |
Therapeutic hypothermia (TH, 32-34°C) has been shown to improve neurological outcome in comatose survivors of out-of-hospital cardiac arrest (OHCA) with ventricular tachycardia or fibrillation. Earlier initiation of TH may increase the beneficial effects. Experimental studies have suggested that starting TH during cardiopulmonary resuscitation (CPR) may further enhance its neuroprotective effects. The aim of this study was to evaluate whether intra-arrest TH (IATH), initiated in the field with trans nasal evaporative cooling (TNEC), would provide outcome benefits when compared to standard of care in patients being resuscitated from OHCA. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United Kingdom | 5 | 28% |
Canada | 2 | 11% |
Australia | 2 | 11% |
New Zealand | 1 | 6% |
Saudi Arabia | 1 | 6% |
Unknown | 7 | 39% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 12 | 67% |
Scientists | 3 | 17% |
Practitioners (doctors, other healthcare professionals) | 3 | 17% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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South Africa | 1 | 1% |
Unknown | 79 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Postgraduate | 10 | 13% |
Student > Master | 10 | 13% |
Student > Bachelor | 10 | 13% |
Student > Ph. D. Student | 8 | 10% |
Student > Doctoral Student | 7 | 9% |
Other | 11 | 14% |
Unknown | 24 | 30% |
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Nursing and Health Professions | 7 | 9% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 3% |
Agricultural and Biological Sciences | 1 | 1% |
Economics, Econometrics and Finance | 1 | 1% |
Other | 8 | 10% |
Unknown | 26 | 33% |