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The effects of Eculizumab on the pathology of malignant atrophic papulosis

Overview of attention for article published in Orphanet Journal of Rare Diseases, November 2013
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Title
The effects of Eculizumab on the pathology of malignant atrophic papulosis
Published in
Orphanet Journal of Rare Diseases, November 2013
DOI 10.1186/1750-1172-8-185
Pubmed ID
Authors

Cynthia M Magro, Xuan Wang, Francine Garrett-Bakelman, Jeffrey Laurence, Lee S Shapiro, Maria T DeSancho

Abstract

Degos disease is a frequently fatal and incurable occlusive vasculopathy most commonly affecting the skin, gastrointestinal tract and brain. Vascular C5b-9 deposition and a type I interferon (IFN) rich microenvironment are held to be pathogenetically important in the evolution of the vascular changes. We recently discovered the use of eculizumab as a salvage drug in the treatment of near fatal Malignant atrophic papulosis (MAP). The effects of eculizumab on the pathology of MAP are explored.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 35 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Czechia 1 3%
Unknown 34 97%

Demographic breakdown

Readers by professional status Count As %
Other 9 26%
Researcher 7 20%
Student > Master 3 9%
Student > Bachelor 2 6%
Librarian 2 6%
Other 7 20%
Unknown 5 14%
Readers by discipline Count As %
Medicine and Dentistry 17 49%
Pharmacology, Toxicology and Pharmaceutical Science 3 9%
Nursing and Health Professions 3 9%
Agricultural and Biological Sciences 3 9%
Biochemistry, Genetics and Molecular Biology 1 3%
Other 2 6%
Unknown 6 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 November 2013.
All research outputs
#17,285,668
of 25,374,647 outputs
Outputs from Orphanet Journal of Rare Diseases
#2,051
of 3,105 outputs
Outputs of similar age
#204,869
of 319,946 outputs
Outputs of similar age from Orphanet Journal of Rare Diseases
#36
of 43 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,105 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.2. This one is in the 26th percentile – i.e., 26% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 319,946 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 43 others from the same source and published within six weeks on either side of this one. This one is in the 13th percentile – i.e., 13% of its contemporaries scored the same or lower than it.