Title |
Open-label trial and randomized, double-blind, placebo-controlled, crossover trial of hydrogen-enriched water for mitochondrial and inflammatory myopathies
|
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Published in |
Medical Gas Research, October 2011
|
DOI | 10.1186/2045-9912-1-24 |
Pubmed ID | |
Authors |
Mikako Ito, Tohru Ibi, Ko Sahashi, Masashi Ichihara, Masafumi Ito, Kinji Ohno |
Abstract |
Molecular hydrogen has prominent effects on more than 30 animal models especially of oxidative stress-mediated diseases and inflammatory diseases. In addition, hydrogen effects on humans have been reported in diabetes mellitus type 2, hemodialysis, metabolic syndrome, radiotherapy for liver cancer, and brain stem infarction. Hydrogen effects are ascribed to specific radical-scavenging activities that eliminate hydroxyl radical and peroxynitrite, and also to signal-modulating activities, but the detailed molecular mechanisms still remain elusive. Hydrogen is a safe molecule that is largely produced by intestinal bacteria in rodents and humans, and no adverse effects have been documented. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 4 | 57% |
Japan | 1 | 14% |
Unknown | 2 | 29% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 6 | 86% |
Practitioners (doctors, other healthcare professionals) | 1 | 14% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Russia | 1 | 1% |
Unknown | 76 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 15 | 19% |
Student > Master | 13 | 17% |
Other | 7 | 9% |
Student > Bachelor | 7 | 9% |
Student > Ph. D. Student | 5 | 6% |
Other | 11 | 14% |
Unknown | 19 | 25% |
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Medicine and Dentistry | 25 | 32% |
Neuroscience | 6 | 8% |
Nursing and Health Professions | 5 | 6% |
Agricultural and Biological Sciences | 3 | 4% |
Pharmacology, Toxicology and Pharmaceutical Science | 3 | 4% |
Other | 9 | 12% |
Unknown | 26 | 34% |