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High performance microbiological transformation of L-tyrosine to L-dopa by Yarrowia lipolyticaNRRL-143

Overview of attention for article published in BMC Biotechnology, August 2007
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Title
High performance microbiological transformation of L-tyrosine to L-dopa by Yarrowia lipolyticaNRRL-143
Published in
BMC Biotechnology, August 2007
DOI 10.1186/1472-6750-7-50
Pubmed ID
Authors

Sikander Ali, Jeffry L Shultz, Ikram-ul-Haq

Abstract

The 3,4-dihydroxy phenyl L-alanine (L-dopa) is a drug of choice for Parkinson's disease, controlling changes in energy metabolism enzymes of the myocardium following neurogenic injury. Aspergillus oryzae is commonly used for L-dopa production; however, potential improvements in ease of handling, growth rate and environmental impact have led to an interest in exploiting alternative yeasts. The two important elements required for L-dopa production are intracellular tyrosinases (thus pre-grown yeast cells are required for the transformation of L-tyrosine to L-dopa) and L-ascorbate, which acts as a reducing agent.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 58 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
France 1 2%
Australia 1 2%
Unknown 56 97%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 16 28%
Researcher 12 21%
Student > Master 4 7%
Student > Doctoral Student 4 7%
Student > Bachelor 4 7%
Other 10 17%
Unknown 8 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 23 40%
Biochemistry, Genetics and Molecular Biology 13 22%
Unspecified 2 3%
Immunology and Microbiology 2 3%
Chemistry 2 3%
Other 6 10%
Unknown 10 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 November 2013.
All research outputs
#17,286,645
of 25,374,917 outputs
Outputs from BMC Biotechnology
#709
of 982 outputs
Outputs of similar age
#61,520
of 70,815 outputs
Outputs of similar age from BMC Biotechnology
#9
of 9 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 982 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.8. This one is in the 21st percentile – i.e., 21% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 70,815 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 7th percentile – i.e., 7% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one.