Title |
Novel method using hybrid markers: development of an approach for pulmonary measurement of multi-walled carbon nanotubes
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Published in |
Journal of Occupational Medicine and Toxicology, October 2013
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DOI | 10.1186/1745-6673-8-30 |
Pubmed ID | |
Authors |
Makoto Ohnishi, Hirofumi Yajima, Tatsuya Kasai, Yumi Umeda, Masahiro Yamamoto, Seigo Yamamoto, Hirokazu Okuda, Masaaki Suzuki, Tomoshi Nishizawa, Shoji Fukushima |
Abstract |
Multi-walled carbon nanotubes (MWCNT)s are suspected to induce pulmonary and pleural cancers due to their asbestos-like configurations. Therefore, accurate measurement of inhaled nanotubes in target organs is crucial for assessing cancer risk. Conventionally, nanotubes are measured after combustion at high temperature for conversion into CO2; however, the sensitivity is poor and the method lacks versatility. We have therefore developed a novel approach using hybrid markers for nanotube analysis, featuring high sensitivity and the capacity to conduct repeated analyses. The method involves adsorption of markers to nanotubes, followed by their desorption and assessment by means of high performance liquid chromatography (HPLC). |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
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Hong Kong | 1 | 14% |
Unknown | 6 | 86% |
Demographic breakdown
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Researcher | 2 | 29% |
Student > Bachelor | 1 | 14% |
Student > Doctoral Student | 1 | 14% |
Student > Master | 1 | 14% |
Professor > Associate Professor | 1 | 14% |
Other | 0 | 0% |
Unknown | 1 | 14% |
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Agricultural and Biological Sciences | 1 | 14% |
Pharmacology, Toxicology and Pharmaceutical Science | 1 | 14% |
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Engineering | 1 | 14% |
Other | 0 | 0% |
Unknown | 1 | 14% |