Title |
The Clostridium small RNome that responds to stress: the paradigm and importance of toxic metabolite stress in C. acetobutylicum
|
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Published in |
BMC Genomics, December 2013
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DOI | 10.1186/1471-2164-14-849 |
Pubmed ID | |
Authors |
Keerthi P Venkataramanan, Shawn W Jones, Kevin P McCormick, Sridhara G Kunjeti, Matthew T Ralston, Blake C Meyers, Eleftherios T Papoutsakis |
Abstract |
Small non-coding RNAs (sRNA) are emerging as major components of the cell's regulatory network, several possessing their own regulons. A few sRNAs have been reported as being involved in general or toxic-metabolite stress, mostly in Gram- prokaryotes, but hardly any in Gram+ prokaryotes. Significantly, the role of sRNAs in the stress response remains poorly understood at the genome-scale level. It was previously shown that toxic-metabolite stress is one of the most comprehensive and encompassing stress responses in the cell, engaging both the general stress (or heat-shock protein, HSP) response as well as specialized metabolic programs. |
X Demographics
Geographical breakdown
Country | Count | As % |
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France | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Scientists | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 1 | 1% |
Netherlands | 1 | 1% |
Brazil | 1 | 1% |
Unknown | 74 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 21 | 27% |
Researcher | 16 | 21% |
Student > Bachelor | 7 | 9% |
Student > Doctoral Student | 5 | 6% |
Professor > Associate Professor | 5 | 6% |
Other | 13 | 17% |
Unknown | 10 | 13% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 36 | 47% |
Biochemistry, Genetics and Molecular Biology | 14 | 18% |
Chemical Engineering | 5 | 6% |
Computer Science | 3 | 4% |
Engineering | 3 | 4% |
Other | 4 | 5% |
Unknown | 12 | 16% |