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Mendeley readers
| Title |
Bacterial serine protease HtrA as a promising new target for antimicrobial therapy?
|
|---|---|
| Published in |
Cell Communication and Signaling, January 2017
|
| DOI | 10.1186/s12964-017-0162-5 |
| Pubmed ID | |
| Authors |
Silja Wessler, Gisbert Schneider, Steffen Backert |
| Abstract |
Recent studies have demonstrated that the bacterial chaperone and serine protease high temperature requirement A (HtrA) is closely associated with the establishment and progression of several infectious diseases. HtrA activity enhances bacterial survival under stress conditions, but also has direct effects on functions of the cell adhesion protein E-cadherin and extracellular matrix proteins, including fibronectin and proteoglycans. Although HtrA cannot be considered as a pathogenic factor per se, it exhibits favorable characteristics making HtrA a potentially attractive drug target to combat various bacterial infections. |
Mendeley readers
The data shown below were compiled from readership statistics for 59 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 2% |
| Unknown | 58 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 13 | 22% |
| Student > Ph. D. Student | 10 | 17% |
| Student > Master | 8 | 14% |
| Researcher | 8 | 14% |
| Student > Postgraduate | 4 | 7% |
| Other | 4 | 7% |
| Unknown | 12 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 17 | 29% |
| Agricultural and Biological Sciences | 10 | 17% |
| Immunology and Microbiology | 7 | 12% |
| Medicine and Dentistry | 5 | 8% |
| Chemistry | 3 | 5% |
| Other | 3 | 5% |
| Unknown | 14 | 24% |