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Production and purification of polymerization-competent HIV-1 capsid protein p24 (CA) in NiCo21(DE3) Escherichia coli

Overview of attention for article published in BMC Biotechnology, December 2013
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Title
Production and purification of polymerization-competent HIV-1 capsid protein p24 (CA) in NiCo21(DE3) Escherichia coli
Published in
BMC Biotechnology, December 2013
DOI 10.1186/1472-6750-13-107
Pubmed ID
Authors

Sin Yeang Teow, Siti Aisyah Mualif, Tasyriq Che Omar, Chew Yik Wei, Narazah Mohd Yusoff, Syed A Ali

Abstract

HIV genome is packaged and organized in a conical capsid, which is made up of ~1,500 copies of the viral capsid protein p24 (CA). Being a primary structural component and due to its critical roles in both late and early stages of the HIV replication cycle, CA has attracted increased interest as a drug discovery target in recent years. Drug discovery studies require large amounts of highly pure and biologically active protein. It is therefore desirable to establish a simple and reproducible process for efficient production of HIV-1 CA.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 47 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 47 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 9 19%
Student > Master 6 13%
Researcher 6 13%
Student > Bachelor 5 11%
Student > Doctoral Student 3 6%
Other 6 13%
Unknown 12 26%
Readers by discipline Count As %
Agricultural and Biological Sciences 13 28%
Biochemistry, Genetics and Molecular Biology 6 13%
Immunology and Microbiology 3 6%
Chemistry 2 4%
Medicine and Dentistry 2 4%
Other 8 17%
Unknown 13 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 December 2013.
All research outputs
#20,211,690
of 22,733,113 outputs
Outputs from BMC Biotechnology
#846
of 935 outputs
Outputs of similar age
#267,247
of 306,889 outputs
Outputs of similar age from BMC Biotechnology
#19
of 19 outputs
Altmetric has tracked 22,733,113 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 935 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.7. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 306,889 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 19 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.