Title |
Clinical characteristics of eosinophilic COPD versus COPD patients with a history of asthma
|
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Published in |
Respiratory Research, April 2017
|
DOI | 10.1186/s12931-017-0559-0 |
Pubmed ID | |
Authors |
Umme Kolsum, Arjun Ravi, Paul Hitchen, Satyanarayana Maddi, Thomas Southworth, Dave Singh |
Abstract |
Eosinophilic COPD appears to be a distinct patient subgroup with an increased corticosteroid response. Eosinophilic COPD has been labelled as part of the asthma COPD overlap syndrome (ACOS). We compared the clinical characteristics of eosinophilic COPD patients (without any clinical history of asthma) and COPD patients with a childhood history of asthma. COPD patients with asthma were characterised by more allergies and more exacerbations, but less eosinophilic inflammation. While terms such as "ACOS" are used to "lump" patients together, we report distinct differences between eosinophilic COPD and COPD patients with asthma, and propose that these groups should be split rather than lumped. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 3 | 25% |
India | 2 | 17% |
Mexico | 1 | 8% |
Australia | 1 | 8% |
Colombia | 1 | 8% |
Canada | 1 | 8% |
Unknown | 3 | 25% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 7 | 58% |
Practitioners (doctors, other healthcare professionals) | 4 | 33% |
Scientists | 1 | 8% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 45 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 9 | 20% |
Other | 6 | 13% |
Student > Doctoral Student | 3 | 7% |
Lecturer > Senior Lecturer | 2 | 4% |
Student > Bachelor | 2 | 4% |
Other | 8 | 18% |
Unknown | 15 | 33% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 17 | 38% |
Biochemistry, Genetics and Molecular Biology | 4 | 9% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 4% |
Immunology and Microbiology | 1 | 2% |
Computer Science | 1 | 2% |
Other | 0 | 0% |
Unknown | 20 | 44% |