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Mendeley readers
| Title |
Effects of two weeks of metformin treatment on whole-body glycocalyx barrier properties in db/db mice
|
|---|---|
| Published in |
Cardiovascular Diabetology, December 2013
|
| DOI | 10.1186/1475-2840-12-175 |
| Pubmed ID | |
| Authors |
Bart JM Eskens, Coert J Zuurbier, Judith van Haare, Hans Vink, Jurgen WGE van Teeffelen |
| Abstract |
The anti-diabetic drug metformin has been demonstrated to exert a protective effect against vascular complications in diabetes independent of its glucose lowering action. Since the endothelial glycocalyx has been indicated to have important vasculoprotective properties and to be vulnerable to degradation by hyperglycemic conditions, we evaluated in the current study the effect of short-term metformin treatment on whole-body glycocalyx barrier properties in a mouse model of non-insulin dependent diabetes mellitus (db/db mouse). |
Mendeley readers
The data shown below were compiled from readership statistics for 70 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Czechia | 1 | 1% |
| Unknown | 69 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 13 | 19% |
| Student > Ph. D. Student | 10 | 14% |
| Student > Master | 10 | 14% |
| Student > Doctoral Student | 5 | 7% |
| Student > Bachelor | 4 | 6% |
| Other | 12 | 17% |
| Unknown | 16 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 22 | 31% |
| Biochemistry, Genetics and Molecular Biology | 8 | 11% |
| Pharmacology, Toxicology and Pharmaceutical Science | 6 | 9% |
| Agricultural and Biological Sciences | 5 | 7% |
| Chemistry | 3 | 4% |
| Other | 7 | 10% |
| Unknown | 19 | 27% |