↓ Skip to main content

Accurate detection of subclonal single nucleotide variants in whole genome amplified and pooled cancer samples using HaloPlex target enrichment

Overview of attention for article published in BMC Genomics, December 2013
Altmetric Badge

About this Attention Score

  • Good Attention Score compared to outputs of the same age (71st percentile)
  • Good Attention Score compared to outputs of the same age and source (69th percentile)

Mentioned by

twitter
1 X user
patent
1 patent

Citations

dimensions_citation
21 Dimensions

Readers on

mendeley
68 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Accurate detection of subclonal single nucleotide variants in whole genome amplified and pooled cancer samples using HaloPlex target enrichment
Published in
BMC Genomics, December 2013
DOI 10.1186/1471-2164-14-856
Pubmed ID
Authors

Eva C Berglund, Carl Mårten Lindqvist, Shahina Hayat, Elin Övernäs, Niklas Henriksson, Jessica Nordlund, Per Wahlberg, Erik Forestier, Gudmar Lönnerholm, Ann-Christine Syvänen

Abstract

Target enrichment and resequencing is a widely used approach for identification of cancer genes and genetic variants associated with diseases. Although cost effective compared to whole genome sequencing, analysis of many samples constitutes a significant cost, which could be reduced by pooling samples before capture. Another limitation to the number of cancer samples that can be analyzed is often the amount of available tumor DNA. We evaluated the performance of whole genome amplified DNA and the power to detect subclonal somatic single nucleotide variants in non-indexed pools of cancer samples using the HaloPlex technology for target enrichment and next generation sequencing.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 68 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Denmark 2 3%
Netherlands 1 1%
Austria 1 1%
Sweden 1 1%
Australia 1 1%
Spain 1 1%
United States 1 1%
Unknown 60 88%

Demographic breakdown

Readers by professional status Count As %
Researcher 23 34%
Student > Ph. D. Student 14 21%
Other 8 12%
Student > Master 7 10%
Student > Doctoral Student 2 3%
Other 6 9%
Unknown 8 12%
Readers by discipline Count As %
Agricultural and Biological Sciences 30 44%
Biochemistry, Genetics and Molecular Biology 17 25%
Computer Science 5 7%
Medicine and Dentistry 3 4%
Mathematics 1 1%
Other 0 0%
Unknown 12 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 January 2022.
All research outputs
#7,959,659
of 25,373,627 outputs
Outputs from BMC Genomics
#3,479
of 11,244 outputs
Outputs of similar age
#87,926
of 320,229 outputs
Outputs of similar age from BMC Genomics
#58
of 200 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 11,244 research outputs from this source. They receive a mean Attention Score of 4.8. This one has gotten more attention than average, scoring higher than 67% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 320,229 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 200 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.