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The MHC locus and genetic susceptibility to autoimmune and infectious diseases

Overview of attention for article published in Genome Biology, April 2017
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (88th percentile)
  • Average Attention Score compared to outputs of the same age and source

Mentioned by

twitter
26 X users
patent
1 patent
facebook
1 Facebook page
wikipedia
4 Wikipedia pages

Citations

dimensions_citation
417 Dimensions

Readers on

mendeley
551 Mendeley
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Title
The MHC locus and genetic susceptibility to autoimmune and infectious diseases
Published in
Genome Biology, April 2017
DOI 10.1186/s13059-017-1207-1
Pubmed ID
Authors

Vasiliki Matzaraki, Vinod Kumar, Cisca Wijmenga, Alexandra Zhernakova

Abstract

In the past 50 years, variants in the major histocompatibility complex (MHC) locus, also known as the human leukocyte antigen (HLA), have been reported as major risk factors for complex diseases. Recent advances, including large genetic screens, imputation, and analyses of non-additive and epistatic effects, have contributed to a better understanding of the shared and specific roles of MHC variants in different diseases. We review these advances and discuss the relationships between MHC variants involved in autoimmune and infectious diseases. Further work in this area will help to distinguish between alternative hypotheses for the role of pathogens in autoimmune disease development.

X Demographics

X Demographics

The data shown below were collected from the profiles of 26 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 551 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 2 <1%
United States 2 <1%
Netherlands 1 <1%
Russia 1 <1%
Unknown 545 99%

Demographic breakdown

Readers by professional status Count As %
Researcher 94 17%
Student > Ph. D. Student 82 15%
Student > Bachelor 69 13%
Student > Master 62 11%
Other 25 5%
Other 75 14%
Unknown 144 26%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 140 25%
Medicine and Dentistry 80 15%
Agricultural and Biological Sciences 62 11%
Immunology and Microbiology 49 9%
Pharmacology, Toxicology and Pharmaceutical Science 11 2%
Other 49 9%
Unknown 160 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 19. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 April 2023.
All research outputs
#1,935,092
of 25,791,495 outputs
Outputs from Genome Biology
#1,606
of 4,517 outputs
Outputs of similar age
#35,631
of 324,527 outputs
Outputs of similar age from Genome Biology
#30
of 54 outputs
Altmetric has tracked 25,791,495 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,517 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 27.5. This one has gotten more attention than average, scoring higher than 64% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 324,527 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 54 others from the same source and published within six weeks on either side of this one. This one is in the 44th percentile – i.e., 44% of its contemporaries scored the same or lower than it.