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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Sex Differences in Opioid Analgesia and Addiction: Interactions among Opioid Receptors and Estrogen Receptors
|
|---|---|
| Published in |
Molecular Pain, January 2013
|
| DOI | 10.1186/1744-8069-9-45 |
| Pubmed ID | |
| Authors |
Cynthia Wei-Sheng Lee, Ing-Kang Ho |
| Abstract |
Opioids are widely used as the pain reliever and also notorious for being addictive drugs. Sex differences in the opioid analgesia and addiction have been reported and investigated in human subjects and animal models. Yet, the molecular mechanism underlying the differences between males and females is still unclear. Here, we reviewed the literature describing the sex differences in analgesic responses and addiction liabilities to clinically relevant opioids. The reported interactions among opioids, estrogens, opioid receptors, and estrogen receptors are also evaluated. We postulate that the sex differences partly originated from the crosstalk among the estrogen and opioid receptors when stimulated by the exogenous opioids, possibly through common secondary messengers and the downstream gene transcriptional regulators. |
X Demographics
The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 50% |
| Unknown | 3 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 67% |
| Scientists | 1 | 17% |
| Practitioners (doctors, other healthcare professionals) | 1 | 17% |
Mendeley readers
The data shown below were compiled from readership statistics for 137 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | <1% |
| Colombia | 1 | <1% |
| Unknown | 135 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 27 | 20% |
| Student > Ph. D. Student | 21 | 15% |
| Student > Doctoral Student | 14 | 10% |
| Researcher | 14 | 10% |
| Student > Master | 10 | 7% |
| Other | 20 | 15% |
| Unknown | 31 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 30 | 22% |
| Medicine and Dentistry | 17 | 12% |
| Agricultural and Biological Sciences | 13 | 9% |
| Psychology | 12 | 9% |
| Biochemistry, Genetics and Molecular Biology | 9 | 7% |
| Other | 20 | 15% |
| Unknown | 36 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 January 2015.
All research outputs
#14,277,392
of 25,373,627 outputs
Outputs from Molecular Pain
#260
of 669 outputs
Outputs of similar age
#163,718
of 288,991 outputs
Outputs of similar age from Molecular Pain
#13
of 41 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 669 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.1. This one has gotten more attention than average, scoring higher than 60% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 288,991 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 41 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 65% of its contemporaries.