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Validation of a leg movements count and periodic leg movements analysis in a custom polysomnography system

Overview of attention for article published in BMC Neurology, February 2017
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Title
Validation of a leg movements count and periodic leg movements analysis in a custom polysomnography system
Published in
BMC Neurology, February 2017
DOI 10.1186/s12883-017-0821-6
Pubmed ID
Authors

Ambra Stefani, Anna Heidbreder, Heinz Hackner, Birgit Högl

Abstract

Periodic leg movements (PLM) during sleep (PLMS) are considered strongly related to restless legs syndrome (RLS), and are associated with polymorphisms in RLS risk genes. Various software for automatic analysis of PLMS are available, but only few of them have been validated. Aim of this study was to validate a leg movements count and analysis integrated in a commercially available polysomnography (PSG) system against manual scoring. Twenty RLS patients with a PLMS index > 20/h and 20 controls with a PLMS index < 5/h were included. Manual and computerized scoring of leg movements (LM) and PLM was performed according to the standard American Academy of Sleep Medicine (AASM) criteria. LM and PLM indices during sleep and wakefulness, the rate of PLMS associated with respiratory events, intermovement interval and periodicity indices were manually and automatically scored. The correlation between manual and computerized scoring was high for all investigated parameters (Spearman correlation coefficients 0.751-0.996, p < 0.001; intraclass correlation coefficients 0.775-0.999, p < 0.001). Bland-Altman plots showed high agreement between manual and automatic analysis. This study validated an automatic LM count and PLM analysis against the gold standard manual scoring according to AASM criteria. The data demonstrate that the software used in this study has an outstanding performance for computerized LM and PLM scoring, and LM and PLM indices generated with this software can be reliably integrated in the routine PSG report. This automatic analysis is also an excellent tool for research purposes.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 28 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 28 100%

Demographic breakdown

Readers by professional status Count As %
Professor 2 7%
Student > Bachelor 2 7%
Student > Doctoral Student 2 7%
Student > Master 2 7%
Researcher 2 7%
Other 5 18%
Unknown 13 46%
Readers by discipline Count As %
Medicine and Dentistry 4 14%
Neuroscience 2 7%
Pharmacology, Toxicology and Pharmaceutical Science 1 4%
Business, Management and Accounting 1 4%
Arts and Humanities 1 4%
Other 4 14%
Unknown 15 54%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 April 2017.
All research outputs
#15,457,417
of 22,968,808 outputs
Outputs from BMC Neurology
#1,499
of 2,454 outputs
Outputs of similar age
#197,716
of 311,150 outputs
Outputs of similar age from BMC Neurology
#26
of 48 outputs
Altmetric has tracked 22,968,808 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,454 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one is in the 26th percentile – i.e., 26% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 311,150 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 48 others from the same source and published within six weeks on either side of this one. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.