Title |
Validation of the short version of the 10/66 dementia diagnosis in multiethnic Asian older adults in Singapore
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Published in |
BMC Geriatrics, April 2017
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DOI | 10.1186/s12877-017-0475-7 |
Pubmed ID | |
Authors |
Edimansyah Abdin, Janhavi Ajit Vaingankar, Louisa Picco, Boon Yiang Chua, Martin Prince, Siow Ann Chong, Mythily Subramaniam |
Abstract |
To validate the short version of the 10/66 dementia diagnosis against the standard version of the 10/66 dementia diagnosis and clinical diagnosis and examine concurrent validity with the World Health Organisation Disability Assessment schedule and care needs in a multiethnic Asian older adult population in Singapore. Data from the Well-being of the Singapore Elderly study, a nationally representative survey of the older Singapore Resident population aged 60 years and above was used. The validity of the short version of the 10/66 dementia diagnostic criteria derived from the Community Screening Instrument for Dementia, the modified Consortium to Establish a Registry of Alzheimer's Disease 10-word list delayed recall and the EURO-D depression screen were examined against the standard version of the 10/66 dementia diagnosis and clinician diagnosis as a gold standard. Concurrent validity was tested by examining the relationships between the short version 10/66 dementia diagnosis, disability and care needs. A total of 2373 respondents who had completed data on the short version diagnosis were included in this study. The majority (82.63%) of respondents were of Chinese descent, 9.86% were Malays, 6.12% were of Indian descent and 1.39% belonged to other ethnic group. We found the short version 10/66 dementia diagnosis showed almost perfect agreement with the standard version 10/66 dementia diagnosis (kappa = 0.90, AUC = 0.96) and substantial agreement with clinical diagnosis (kappa = 0.70, AUC = 0.87). The weighted prevalence of dementia in the population was slightly higher based on the short version diagnosis than the standard version diagnosis (10.74% vs. 10.04%). We also found that those with the short version 10/66 dementia were significantly associated with higher disability (β = 28.90, 95% CI = 23.62, 9.62) and needed care occasionally (OR =35.21, 95% CI = 18.08, 68.59) or much of the time (OR = 9.02, 95% CI = 5.21, 15.61). The study found that the short version 10/66 dementia diagnosis has excellent validity to diagnose dementia in a multiethnic Asian population in Singapore. Further research is required to determine the usefulness of this diagnosis in clinical practice or institutional settings to aid early detection and intervention for dementia. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 67 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 10 | 15% |
Student > Bachelor | 8 | 12% |
Student > Ph. D. Student | 6 | 9% |
Student > Master | 5 | 7% |
Student > Doctoral Student | 4 | 6% |
Other | 10 | 15% |
Unknown | 24 | 36% |
Readers by discipline | Count | As % |
---|---|---|
Psychology | 8 | 12% |
Medicine and Dentistry | 7 | 10% |
Nursing and Health Professions | 7 | 10% |
Social Sciences | 5 | 7% |
Neuroscience | 3 | 4% |
Other | 8 | 12% |
Unknown | 29 | 43% |