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How reliable is the linear noise approximation of gene regulatory networks?

Overview of attention for article published in BMC Genomics, October 2013
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Title
How reliable is the linear noise approximation of gene regulatory networks?
Published in
BMC Genomics, October 2013
DOI 10.1186/1471-2164-14-s4-s5
Pubmed ID
Authors

Philipp Thomas, Hannes Matuschek, Ramon Grima

Abstract

The linear noise approximation (LNA) is commonly used to predict how noise is regulated and exploited at the cellular level. These predictions are exact for reaction networks composed exclusively of first order reactions or for networks involving bimolecular reactions and large numbers of molecules. It is however well known that gene regulation involves bimolecular interactions with molecule numbers as small as a single copy of a particular gene. It is therefore questionable how reliable are the LNA predictions for these systems.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 58 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
Netherlands 1 2%
Germany 1 2%
Unknown 55 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 15 26%
Student > Ph. D. Student 13 22%
Student > Master 9 16%
Lecturer 3 5%
Student > Bachelor 2 3%
Other 7 12%
Unknown 9 16%
Readers by discipline Count As %
Physics and Astronomy 9 16%
Mathematics 8 14%
Biochemistry, Genetics and Molecular Biology 8 14%
Agricultural and Biological Sciences 7 12%
Computer Science 6 10%
Other 8 14%
Unknown 12 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 December 2013.
All research outputs
#18,357,514
of 22,736,112 outputs
Outputs from BMC Genomics
#8,159
of 10,631 outputs
Outputs of similar age
#154,393
of 207,137 outputs
Outputs of similar age from BMC Genomics
#94
of 148 outputs
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So far Altmetric has tracked 10,631 research outputs from this source. They receive a mean Attention Score of 4.7. This one is in the 12th percentile – i.e., 12% of its peers scored the same or lower than it.
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