Title |
Biochemical and molecular characterization of Treponema phagedenis-like spirochetes isolated from a bovine digital dermatitis lesion
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Published in |
BMC Microbiology, December 2013
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DOI | 10.1186/1471-2180-13-280 |
Pubmed ID | |
Authors |
Jennifer H Wilson-Welder, Margaret K Elliott, Richard L Zuerner, Darrell O Bayles, David P Alt, Thad B Stanton |
Abstract |
Bovine papillomatous digital dermatitis (DD) is the leading cause of lameness in dairy cattle and represents a serious welfare and economic burden. Found primarily in high production dairy cattle worldwide, DD is characterized by the development of an often painful red, raw ulcerative or papillomatous lesion frequently located near the interdigital cleft and above the bulbs of the heel. While the exact etiology is unknown, several spirochete species have been isolated from lesion material. Four isolates of Treponema phagedenis-like spirochetes were isolated from dairy cows in Iowa. Given the distinct differences in host, environmental niche, and disease association, a closer analysis of phenotypic characteristics, growth characteristics, and genomic sequences of T. phagedenis, a human genitalia commensal, and the Iowa DD isolates was undertaken. |
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United States | 1 | 100% |
Demographic breakdown
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
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Brazil | 1 | 2% |
Unknown | 50 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 14 | 27% |
Researcher | 6 | 12% |
Student > Bachelor | 4 | 8% |
Other | 4 | 8% |
Student > Master | 4 | 8% |
Other | 10 | 20% |
Unknown | 9 | 18% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 20 | 39% |
Veterinary Science and Veterinary Medicine | 13 | 25% |
Biochemistry, Genetics and Molecular Biology | 3 | 6% |
Philosophy | 1 | 2% |
Immunology and Microbiology | 1 | 2% |
Other | 4 | 8% |
Unknown | 9 | 18% |