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Enhanced membrane protein expression by engineering increased intracellular membrane production

Overview of attention for article published in Microbial Cell Factories, December 2013
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (71st percentile)
  • Above-average Attention Score compared to outputs of the same age and source (54th percentile)

Mentioned by

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3 X users
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1 research highlight platform

Citations

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35 Dimensions

Readers on

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135 Mendeley
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Title
Enhanced membrane protein expression by engineering increased intracellular membrane production
Published in
Microbial Cell Factories, December 2013
DOI 10.1186/1475-2859-12-122
Pubmed ID
Authors

Mouna Guerfal, Katrien Claes, Oskar Knittelfelder, Riet De Rycke, Sepp D Kohlwein, Nico Callewaert

Abstract

Membrane protein research is frequently hampered by the low natural abundance of these proteins in cells and typically relies on recombinant gene expression. Different expression systems, like mammalian cells, insect cells, bacteria and yeast are being used, but very few research efforts have been directed towards specific host cell customization for enhanced expression of membrane proteins. Here we show that by increasing the intracellular membrane production by interfering with a key enzymatic step of lipid synthesis, enhanced expression of membrane proteins in yeast is achieved.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 135 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Austria 4 3%
Uruguay 1 <1%
Indonesia 1 <1%
Canada 1 <1%
United States 1 <1%
Unknown 127 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 36 27%
Researcher 24 18%
Student > Bachelor 15 11%
Student > Doctoral Student 13 10%
Student > Master 12 9%
Other 21 16%
Unknown 14 10%
Readers by discipline Count As %
Agricultural and Biological Sciences 46 34%
Biochemistry, Genetics and Molecular Biology 41 30%
Engineering 7 5%
Chemical Engineering 4 3%
Chemistry 4 3%
Other 11 8%
Unknown 22 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 January 2014.
All research outputs
#7,126,046
of 22,736,112 outputs
Outputs from Microbial Cell Factories
#486
of 1,589 outputs
Outputs of similar age
#87,455
of 306,960 outputs
Outputs of similar age from Microbial Cell Factories
#20
of 44 outputs
Altmetric has tracked 22,736,112 research outputs across all sources so far. This one has received more attention than most of these and is in the 68th percentile.
So far Altmetric has tracked 1,589 research outputs from this source. They receive a mean Attention Score of 4.4. This one has gotten more attention than average, scoring higher than 69% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 306,960 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 44 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 54% of its contemporaries.