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CD8+T cells from HLA-B*57 elite suppressors effectively suppress replication of HIV-1 escape mutants

Overview of attention for article published in Retrovirology, December 2013
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (75th percentile)
  • Good Attention Score compared to outputs of the same age and source (77th percentile)

Mentioned by

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3 X users
patent
1 patent

Citations

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31 Dimensions

Readers on

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42 Mendeley
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1 CiteULike
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Title
CD8+T cells from HLA-B*57 elite suppressors effectively suppress replication of HIV-1 escape mutants
Published in
Retrovirology, December 2013
DOI 10.1186/1742-4690-10-152
Pubmed ID
Authors

Christopher W Pohlmeyer, Robert W Buckheit, Robert F Siliciano, Joel N Blankson

Abstract

Elite Controllers or Suppressors (ES) are HIV-1 positive individuals who maintain plasma viral loads below the limit of detection of standard clinical assays without antiretroviral therapy. Multiple lines of evidence suggest that the control of viral replication in these patients is due to a strong and specific cytotoxic T lymphocyte (CTL) response. The ability of CD8+ T cells to control HIV-1 replication is believed to be impaired by the development of escape mutations. Surprisingly, viruses amplified from the plasma of ES have been shown to contain multiple escape mutations, and it is not clear how immunologic control is maintained in the face of virologic escape.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 42 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Portugal 1 2%
Germany 1 2%
Unknown 39 93%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 7 17%
Student > Ph. D. Student 7 17%
Researcher 7 17%
Student > Master 5 12%
Student > Doctoral Student 3 7%
Other 5 12%
Unknown 8 19%
Readers by discipline Count As %
Agricultural and Biological Sciences 12 29%
Immunology and Microbiology 10 24%
Biochemistry, Genetics and Molecular Biology 6 14%
Medicine and Dentistry 5 12%
Unknown 9 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 December 2013.
All research outputs
#7,024,485
of 24,896,578 outputs
Outputs from Retrovirology
#348
of 1,142 outputs
Outputs of similar age
#78,911
of 320,135 outputs
Outputs of similar age from Retrovirology
#12
of 53 outputs
Altmetric has tracked 24,896,578 research outputs across all sources so far. This one has received more attention than most of these and is in the 71st percentile.
So far Altmetric has tracked 1,142 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.2. This one has gotten more attention than average, scoring higher than 68% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 320,135 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 75% of its contemporaries.
We're also able to compare this research output to 53 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 77% of its contemporaries.