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A modified oral sugar test for evaluation of insulin and glucose dynamics in horses

Overview of attention for article published in Acta Veterinaria Scandinavica, October 2016
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  • Above-average Attention Score compared to outputs of the same age (63rd percentile)
  • Average Attention Score compared to outputs of the same age and source

Mentioned by

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1 patent
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1 Facebook page

Citations

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18 Dimensions

Readers on

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38 Mendeley
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Title
A modified oral sugar test for evaluation of insulin and glucose dynamics in horses
Published in
Acta Veterinaria Scandinavica, October 2016
DOI 10.1186/s13028-016-0246-z
Pubmed ID
Authors

Sanna Lindåse, Katarina Nostell, Johan Bröjer

Abstract

An oral sugar test (OST) using Karo(®) Light Corn Syrup has been developed in the USA as a field test for the assessment of insulin dysregulation in horses but the syrup is not available in Scandinavian grocery stores. The aim of the study was to compare the results of a modified OST between horses with equine metabolic syndrome (EMS) and healthy horses using a Scandinavian commercially available glucose syrup (Dansukker glykossirap). In addition, the effect of breed and the repeatability of the test were evaluated. In the present study, clinically healthy horses (7 Shetland ponies, 8 Icelandic horses, 8 Standardbred horses) and 20 horses of various breeds with EMS underwent the modified OST test. The Icelandic horses and Shetland ponies underwent the OST twice. Insulin and glucose data from the OST were used to calculate peak insulin concentration (PeakINS), time to peak insulin concentration (T-peakINS), area under the curve for insulin (AUCINS) and glucose (AUCGLU) as well as whole body insulin sensitivity index (ISICOMP). Compared to the healthy group, the EMS group had 6-7 times higher geometric mean for PeakINS and AUCINS and 8 times lower geometric mean for ISICOMP. The EMS group had a delayed T-peakINS compared to the healthy group. There was no effect of breed in the group of healthy horses on PeakINS, T-peakINS, AUCINS, AUCGLU and ISICOMP. Coefficient of variation for repeated tests was 19.8, 19.0 and 17.6 % for PeakINS, AUCINS and ISICOMP respectively. The results of the present study demonstrate that the modified OST appears to be a practical and useful diagnostic tool for assessment of insulin dysregulation in the horse. However, to make it possible to establish the most appropriate sampling interval and to evaluate the accuracy of the modified OST, further studies in horses with a variable degree of insulin resistance are needed, where results from the modified OST are compared with quantitative measurements for IS.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 38 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 3%
Unknown 37 97%

Demographic breakdown

Readers by professional status Count As %
Other 7 18%
Student > Master 4 11%
Researcher 4 11%
Student > Doctoral Student 3 8%
Student > Postgraduate 3 8%
Other 8 21%
Unknown 9 24%
Readers by discipline Count As %
Veterinary Science and Veterinary Medicine 12 32%
Medicine and Dentistry 6 16%
Agricultural and Biological Sciences 3 8%
Nursing and Health Professions 2 5%
Biochemistry, Genetics and Molecular Biology 2 5%
Other 3 8%
Unknown 10 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 July 2020.
All research outputs
#8,261,140
of 25,371,288 outputs
Outputs from Acta Veterinaria Scandinavica
#172
of 836 outputs
Outputs of similar age
#115,561
of 322,956 outputs
Outputs of similar age from Acta Veterinaria Scandinavica
#6
of 11 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one has received more attention than most of these and is in the 66th percentile.
So far Altmetric has tracked 836 research outputs from this source. They receive a mean Attention Score of 3.4. This one has done well, scoring higher than 78% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 322,956 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 63% of its contemporaries.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.