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Will we cure cancer by sequencing thousands of genomes?

Overview of attention for article published in Molecular Cytogenetics, December 2013
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  • Average Attention Score compared to outputs of the same age
  • Good Attention Score compared to outputs of the same age and source (76th percentile)

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4 X users

Citations

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5 Dimensions

Readers on

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9 Mendeley
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Title
Will we cure cancer by sequencing thousands of genomes?
Published in
Molecular Cytogenetics, December 2013
DOI 10.1186/1755-8166-6-57
Pubmed ID
Authors

Joshua M Nicholson

Abstract

The promise to understand cancer and develop efficacious therapies by sequencing thousands of cancers has not occurred. Mutations in specific genes termed oncogenes and tumor suppressor genes are extremely heterogeneous amongst the same type of cancer as well as between cancers. They provide little selective advantage to the cancer and in functional tests have yet to be shown to be sufficient for transformation. Here I discuss the karyotyptic theory of cancer and ask if it is time for a new approach to understanding and ultimately treating cancer.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 9 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Ukraine 1 11%
Unknown 8 89%

Demographic breakdown

Readers by professional status Count As %
Researcher 3 33%
Student > Ph. D. Student 2 22%
Lecturer > Senior Lecturer 1 11%
Student > Doctoral Student 1 11%
Student > Master 1 11%
Other 1 11%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 4 44%
Agricultural and Biological Sciences 3 33%
Medicine and Dentistry 1 11%
Engineering 1 11%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 December 2013.
All research outputs
#15,740,505
of 25,374,917 outputs
Outputs from Molecular Cytogenetics
#122
of 423 outputs
Outputs of similar age
#185,391
of 320,429 outputs
Outputs of similar age from Molecular Cytogenetics
#9
of 38 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 423 research outputs from this source. They receive a mean Attention Score of 2.4. This one has gotten more attention than average, scoring higher than 70% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 320,429 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 41st percentile – i.e., 41% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 38 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 76% of its contemporaries.