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Statins and therapy of Alzheimer's disease: questions of efficacy versus trial design

Overview of attention for article published in Alzheimer's Research & Therapy, January 2012
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1 Facebook page

Citations

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9 Dimensions

Readers on

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16 Mendeley
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1 CiteULike
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Title
Statins and therapy of Alzheimer's disease: questions of efficacy versus trial design
Published in
Alzheimer's Research & Therapy, January 2012
DOI 10.1186/alzrt101
Pubmed ID
Authors

Benjamin Wolozin

Abstract

Recent trials of statins produced no benefit for subjects with Alzheimer's disease. These negative studies add to a growing list of negative clinical trials. These data point to a need for reevaluating the pathophysiology of late-onset Alzheimer's disease. Late-onset Alzheimer's disease might result from the cumulative effects of at least four different factors: β-amyloid accumulation, cardiovascular disease, aging and the associated loss of synaptic plasticity, and inflammation. Successful therapy of subjects with overt dementia might require approaches targeting all four pathophysiological domains.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 16 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 16 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 3 19%
Researcher 3 19%
Professor > Associate Professor 3 19%
Student > Bachelor 2 13%
Student > Master 1 6%
Other 3 19%
Unknown 1 6%
Readers by discipline Count As %
Agricultural and Biological Sciences 5 31%
Neuroscience 3 19%
Psychology 2 13%
Medicine and Dentistry 2 13%
Immunology and Microbiology 1 6%
Other 1 6%
Unknown 2 13%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 December 2013.
All research outputs
#22,758,309
of 25,373,627 outputs
Outputs from Alzheimer's Research & Therapy
#1,434
of 1,464 outputs
Outputs of similar age
#229,110
of 251,075 outputs
Outputs of similar age from Alzheimer's Research & Therapy
#8
of 9 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,464 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 26.6. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 251,075 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 9 others from the same source and published within six weeks on either side of this one.