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From inflammation to gastric cancer – the importance of Hedgehog/GLI signaling in Helicobacter pylori-induced chronic inflammatory and neoplastic diseases

Overview of attention for article published in Cell Communication and Signaling, April 2017
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (82nd percentile)
  • High Attention Score compared to outputs of the same age and source (99th percentile)

Mentioned by

news
1 news outlet
twitter
1 X user

Citations

dimensions_citation
71 Dimensions

Readers on

mendeley
53 Mendeley
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Title
From inflammation to gastric cancer – the importance of Hedgehog/GLI signaling in Helicobacter pylori-induced chronic inflammatory and neoplastic diseases
Published in
Cell Communication and Signaling, April 2017
DOI 10.1186/s12964-017-0171-4
Pubmed ID
Authors

Silja Wessler, Linda M. Krisch, Dominik P. Elmer, Fritz Aberger

Abstract

Infections with the human pathogen Helicobacter pylori (H. pylori) are closely associated with the development of inflammatory disorders and neoplastic transformation of the gastric epithelium. Drastic changes in the micromilieu involve a complex network of H. pylori-regulated signal transduction pathways leading to the release of proinflammatory cytokines, gut hormones and a wide range of signaling molecules. Besides controlling embryonic development, the Hedgehog/GLI signaling pathway also plays important roles in epithelial proliferation, differentiation, and regeneration of the gastric physiology, but also in the induction and progression of inflammation and neoplastic transformation in H. pylori infections. Here, we summarize recent findings of H. pylori-associated Hedgehog/GLI signaling in gastric homeostasis, malignant development and the modulation of the gastric tumor microenvironment.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 53 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Poland 1 2%
Unknown 52 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 10 19%
Student > Master 8 15%
Researcher 8 15%
Student > Doctoral Student 5 9%
Student > Bachelor 5 9%
Other 6 11%
Unknown 11 21%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 17 32%
Agricultural and Biological Sciences 7 13%
Medicine and Dentistry 5 9%
Immunology and Microbiology 5 9%
Pharmacology, Toxicology and Pharmaceutical Science 2 4%
Other 4 8%
Unknown 13 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 April 2022.
All research outputs
#3,053,262
of 24,093,053 outputs
Outputs from Cell Communication and Signaling
#61
of 1,162 outputs
Outputs of similar age
#54,999
of 313,777 outputs
Outputs of similar age from Cell Communication and Signaling
#1
of 5 outputs
Altmetric has tracked 24,093,053 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,162 research outputs from this source. They receive a mean Attention Score of 3.8. This one has done particularly well, scoring higher than 94% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 313,777 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 82% of its contemporaries.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them