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Naturally occurring resistance mutations to inhibitors of HCV NS5A region and NS5B polymerase in DAA treatment-naïve patients

Overview of attention for article published in Virology Journal, December 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (87th percentile)
  • High Attention Score compared to outputs of the same age and source (86th percentile)

Mentioned by

blogs
1 blog
twitter
4 X users
facebook
1 Facebook page

Citations

dimensions_citation
81 Dimensions

Readers on

mendeley
88 Mendeley
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Title
Naturally occurring resistance mutations to inhibitors of HCV NS5A region and NS5B polymerase in DAA treatment-naïve patients
Published in
Virology Journal, December 2013
DOI 10.1186/1743-422x-10-355
Pubmed ID
Authors

Stefania Paolucci, Loretta Fiorina, Bianca Mariani, Roberto Gulminetti, Stefano Novati, Giorgio Barbarini, Raffaele Bruno, Fausto Baldanti

Abstract

Direct-acting antiviral (DAA) agents target HCV proteins; some of these have already been approved for the treatment of HCV infection, while others are in development. However, selection of DAA-resistant viral variants may hamper treatment. The aim of this study was to illustrate potential natural DAA-resistance mutations in the HCV NS5A and NS5B regions of HCV genotypes 1a and 1b from DAA-naïve patients.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 88 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Sweden 1 1%
Unknown 87 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 16 18%
Researcher 11 13%
Other 9 10%
Professor > Associate Professor 9 10%
Student > Master 9 10%
Other 17 19%
Unknown 17 19%
Readers by discipline Count As %
Medicine and Dentistry 26 30%
Agricultural and Biological Sciences 14 16%
Biochemistry, Genetics and Molecular Biology 10 11%
Immunology and Microbiology 9 10%
Chemical Engineering 3 3%
Other 7 8%
Unknown 19 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 December 2013.
All research outputs
#3,150,168
of 22,736,112 outputs
Outputs from Virology Journal
#304
of 3,035 outputs
Outputs of similar age
#35,933
of 286,036 outputs
Outputs of similar age from Virology Journal
#7
of 53 outputs
Altmetric has tracked 22,736,112 research outputs across all sources so far. Compared to these this one has done well and is in the 86th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,035 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 25.6. This one has done well, scoring higher than 89% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 286,036 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 87% of its contemporaries.
We're also able to compare this research output to 53 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 86% of its contemporaries.