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The roles of microRNAs in regulation of mammalian spermatogenesis

Overview of attention for article published in Journal of Animal Science and Biotechnology, May 2017
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Title
The roles of microRNAs in regulation of mammalian spermatogenesis
Published in
Journal of Animal Science and Biotechnology, May 2017
DOI 10.1186/s40104-017-0166-4
Pubmed ID
Authors

Xiaoxu Chen, Xueliang Li, Jiayin Guo, Pengfei Zhang, Wenxian Zeng

Abstract

Mammalian spermatogenesis contains three continuous and organized processes, by which spermatogonia undergo mitosis and differentiate to spermatocytes, follow on meiosis to form haploid spermatids and ultimately transform into spermatozoa. These processes require an accurately, spatially and temporally regulated gene expression patterns. The microRNAs are a novel class of post-transcriptional regulators. Cumulating evidences have demonstrated that microRNAs are expressed in a cell-specific or stage-specific manner during spermatogenesis. In this review, we focus on the roles of microRNAs in spermatogenesis. We highlight that N6-methyladenosine (m6A) is involved in the biogenesis of microRNAs and miRNA regulates the m6A modification on mRNA, and that specific miRNAs have been exploited as potential biomarkers for the male factor infertility, which will provide insightful understanding of microRNA roles in spermatogenesis.

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The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 115 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 115 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 20 17%
Student > Master 14 12%
Student > Bachelor 14 12%
Researcher 13 11%
Student > Doctoral Student 8 7%
Other 20 17%
Unknown 26 23%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 31 27%
Agricultural and Biological Sciences 21 18%
Medicine and Dentistry 16 14%
Veterinary Science and Veterinary Medicine 5 4%
Chemistry 3 3%
Other 8 7%
Unknown 31 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 May 2017.
All research outputs
#17,289,387
of 25,382,440 outputs
Outputs from Journal of Animal Science and Biotechnology
#456
of 904 outputs
Outputs of similar age
#206,650
of 324,557 outputs
Outputs of similar age from Journal of Animal Science and Biotechnology
#14
of 24 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 904 research outputs from this source. They receive a mean Attention Score of 3.3. This one is in the 35th percentile – i.e., 35% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 324,557 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 24 others from the same source and published within six weeks on either side of this one. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.