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Loss of IP3 receptor function in neuropeptide secreting neurons leads to obesity in adult Drosophila

Overview of attention for article published in BMC Neuroscience, December 2013
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Title
Loss of IP3 receptor function in neuropeptide secreting neurons leads to obesity in adult Drosophila
Published in
BMC Neuroscience, December 2013
DOI 10.1186/1471-2202-14-157
Pubmed ID
Authors

Manivannan Subramanian, Siddharth Jayakumar, Shlesha Richhariya, Gaiti Hasan

Abstract

Intracellular calcium signaling regulates a variety of cellular and physiological processes. The inositol 1,4,5 trisphosphate receptor (IP3R) is a ligand gated calcium channel present on the membranes of endoplasmic reticular stores. In previous work we have shown that Drosophila mutants for the IP3R (itprku) become unnaturally obese as adults with excessive storage of lipids on a normal diet. While the phenotype manifests in cells of the fat body, genetic studies suggest dysregulation of a neurohormonal axis.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 48 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 2 4%
India 1 2%
Unknown 45 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 15 31%
Researcher 11 23%
Student > Bachelor 4 8%
Professor 4 8%
Student > Master 2 4%
Other 5 10%
Unknown 7 15%
Readers by discipline Count As %
Agricultural and Biological Sciences 18 38%
Biochemistry, Genetics and Molecular Biology 12 25%
Neuroscience 4 8%
Medicine and Dentistry 4 8%
Psychology 2 4%
Other 0 0%
Unknown 8 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 December 2013.
All research outputs
#19,015,492
of 23,577,654 outputs
Outputs from BMC Neuroscience
#900
of 1,264 outputs
Outputs of similar age
#234,714
of 309,809 outputs
Outputs of similar age from BMC Neuroscience
#30
of 35 outputs
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So far Altmetric has tracked 1,264 research outputs from this source. They receive a mean Attention Score of 4.4. This one is in the 14th percentile – i.e., 14% of its peers scored the same or lower than it.
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