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Late thrombosis of a mitral bioprosthetic valve with associated massive left atrial thrombus

Overview of attention for article published in Echo Research & Practice, March 2017
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  • In the top 5% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#25 of 268)
  • High Attention Score compared to outputs of the same age (93rd percentile)
  • Average Attention Score compared to outputs of the same age and source

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Title
Late thrombosis of a mitral bioprosthetic valve with associated massive left atrial thrombus
Published in
Echo Research & Practice, March 2017
DOI 10.1530/erp-17-0004
Pubmed ID
Authors

Preetham R. Muskula, Rigoberto Ramirez, A. Michael Borkon, Michael L. Main

Abstract

An 84-year-old man presented 5 years following bioprosthetic mitral valve replacement with three months of worsening dyspnea on exertion. A new mitral stenosis murmur was noted on physical examination, and an electrocardiogram revealed newly recognized atrial fibrillation. Severe mitral stenosis (mean gradient = 13 mmHg) was confirmed by transthoracic echocardiography. Transesophageal echocardiography revealed markedly thickened mitral bioprosthetic leaflets with limited mobility, and a massive left atrial thrombus (> 4 cm in diameter) (see Figures 1A-D, and video files 1-4). Intravenous heparin was initiated, and 5 days later he was taken to the operating room for planned redo mitral valve replacement and left atrial thrombus extraction. Intraoperative transesophageal echocardiography revealed near complete resolution of the bioprosthetic leaflet thickening, and a mean mitral gradient of only 3 mmHg (see Figures 2A-C and multimedia files 5- 7). The patient underwent resection of the massive left atrial thrombus (see Figure 2D), but did not require redo mitral valve replacement. He was initiated on heparin (and transitioned to warfarin) early in the post-operative period, with complete resolution of dyspnea on exertion at 3 month follow-up. Bioprosthetic valve thrombosis is increasingly recognized as a cause of early prosthetic valve dysfunction (1, 2). This case illustrates that bioprosthetic valve thrombosis may occur years following valve replacement, therefore, any deterioration in the patients' clinical status (new onset dyspnea, heart failure, atrial fibrillation) warrants a thorough evaluation of the bioprosthetic valve with transesophageal echocardiography. In this case, initiation of anticoagulation obviated the need for redo mitral valve replacement.

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Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 38. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 November 2017.
All research outputs
#1,077,462
of 25,382,440 outputs
Outputs from Echo Research & Practice
#25
of 268 outputs
Outputs of similar age
#21,895
of 322,508 outputs
Outputs of similar age from Echo Research & Practice
#4
of 8 outputs
Altmetric has tracked 25,382,440 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 268 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.3. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 322,508 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 8 others from the same source and published within six weeks on either side of this one. This one has scored higher than 4 of them.